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TranscriptomicsGlobal transcriptomic profiling of lactacystin-mediated neuronal death
Inhibition of proteasome degradation pathway has been implicated in neuronal cell death leading to neurodegenerative diseases such as ParkinsonM-bM-^@M-^Ys disease and AlzheimerM-bM-^@M-^Ys disease. Pharmacological proteasomal inhibitors such as lactacystin can induce apoptosis in cultured mouse co...
ORGANISM(S): Mus musculus 
2012-01-03 | E-GEOD-22465 | biostudies-arrayexpress
ProteomicsDependence of Synaptic Protein Degradation on Proteasomal Function
Synaptic function crucially depends on uninterrupted synthesis and degradation of synaptic proteins. While much has been learned on synaptic protein synthesis, little is known on the routes by which synaptic proteins are degraded. Here we systematically studied how inhibition of the ubiquitin-protea...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-10-26 | PXD004813 | Pride
Proteomics Synaptic protein Degradation 
UnknownProteasomal inhibition triggers viral oncoprotein degradation via autophagy-lysosomal pathway.
Not available
S-EPMC7058366 | biostudies-literature
ProteomicsDependence of Synaptic Protein Degradation on Proteasomal Function -Part3
Synaptic function crucially depends on uninterrupted synthesis and degradation of synaptic proteins. While much has been learned on synaptic protein synthesis, little is known on the routes by which synaptic proteins are degraded. Here we systematically studied how inhibition of the ubiquitin-protea...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-10-26 | PXD004711 | Pride
Proteomics Synaptic protein Degradation 
ProteomicsDependence of Synaptic Protein Degradation on Proteasomal Function -Part2
Synaptic function crucially depends on uninterrupted synthesis and degradation of synaptic proteins. While much has been learned on synaptic protein synthesis, little is known on the routes by which synaptic proteins are degraded. Here we systematically studied how inhibition of the ubiquitin-protea...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-10-26 | PXD004726 | Pride
Proteomics Synaptic protein Degradation 
GenomicsInhibition of Virally-Induced TFEB Proteasomal Degradation as a Host-Centric Therapeutic Approach for Coronaviral Infection
Inhibition of Virally-Induced TFEB Proteasomal Degradation as a Host-Centric Therapeutic Approach for Coronaviral Infection
PRJNA1242282 | ENA
UnknownElevation of proteasomal substrate levels sensitizes cells to apoptosis induced by inhibition of proteasomal deubiquitinases.
Not available
S-EPMC4186810 | biostudies-literature
UnknownProteasomal Inhibition Redirects the PrP-Like Shadoo Protein to the Nucleus.
Not available
S-EPMC6815274 | biostudies-literature
Genomics PARG regulates the proteasomal degradation of TARG1
 PARG regulates the proteasomal degradation of TARG1
PRJNA1367021 | ENA
UnknownPDE1 inhibition facilitates proteasomal degradation of misfolded proteins and protects against cardiac proteinopathy.
Not available
S-EPMC6531002 | biostudies-literature
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