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TranscriptomicsClarifying the translational pausing landscape in bacteria by ribosome profiling
The rate of protein synthesis varies according to the mRNA sequence in ways that affect gene expression. Global analysis of translational pausing is now possible with ribosome profiling. Here, we revisit an earlier report that Shine-Dalgarno sequences are the major determinant of translational pausi...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2016-01-13 | E-GEOD-72899 | biostudies-arrayexpress
TranscriptomicsTranslational profiling in the unfolded protein response
The unfolded protein response (UPR) couples cellular translation rates and gene expression to the protein folding status of the endoplasmic reticulum (ER). Upon activation, the UPR machinery elicits a general suppression of protein synthesis and activation of stress gene expression, which act coordi...
ORGANISM(S): Mus musculus 
2014-08-28 | E-GEOD-53743 | biostudies-arrayexpress
UnknownThe C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome.
Not available
S-EPMC2632931 | biostudies-literature
GenomicsCotranslational assembly of protein complexes in eukaryotes revealed by ribosome profiling
Cotranslational assembly of protein complexes in eukaryotes revealed by ribosome profiling
PRJNA479682 | ENA
GenomicsFibrillarin regulates oncogenic protein pools and ribosome protein composition in triple-negative breast cancer
Fibrillarin regulates oncogenic protein pools and ribosome protein composition in triple-negative breast cancer
PRJNA1140103 | ENA
UnknownMaize ribosome-inactivating protein uses Lys158-lys161 to interact with ribosomal protein P2 and the strength of interaction is correlated to the biological activities.
Not available
S-EPMC3520970 | biostudies-literature
TranscriptomicsGenome-wide analysis of Musashi-2 targets reveals novel functions in governing epithelial cell migration
The Musashi-2 (Msi2) RNA-binding protein maintains stem cell self-renewal and promotes oncogenesis by enhancing cell proliferation in hematopoietic and gastrointestinal tissues. However, it is unclear how Msi2 recognizes and regulates mRNA targets in vivo and whether Msi2 primarily controls cell gro...
ORGANISM(S): Mus musculus 
2016-04-01 | E-GEOD-71333 | biostudies-arrayexpress
UnknownCrystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2.
Not available
S-EPMC5086656 | biostudies-literature
UnknownInteraction between trichosanthin, a ribosome-inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses.
Not available
S-EPMC1865052 | biostudies-literature
UnknownStructural Dynamics of the YidC:Ribosome Complex during Membrane Protein Biogenesis.
Not available
S-EPMC5186731 | biostudies-literature
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