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TranscriptomicsExpression data from RECK-overexpressing HT1080 fibrosarcoma cells
RECK, a glycosylphosphatidylinositol-anchored glycoprotein, inhibits the enzymatic activities of some matrix metalloproteinases (MMP), thereby suppressing tumor cell metastasis; however, the detailed mechanism is still obscure. In this study, we compared the gene expression profiles between mock- an...
ORGANISM(S): Homo sapiens 
2010-04-14 | E-GEOD-21306 | biostudies-arrayexpress
TranscriptomicsExpression data from RECK-overexpressing HT1080 fibrosarcoma cells
RECK, a glycosylphosphatidylinositol-anchored glycoprotein, inhibits the enzymatic activities of some matrix metalloproteinases (MMP), thereby suppressing tumor cell metastasis; however, the detailed mechanism is still obscure. In this study, we compared the gene expression profiles between mock- an...
ORGANISM(S): Homo sapiens 
2010-04-14 | GSE21306 | GEO
TranscriptomicsRECK Controls Breast Cancer Metastasis by Modulating a Convergent, STAT3-dependent Neoangiogenic Switch
Metastasis leads to the majority of deaths in breast cancer patients. Here we investigated the molecular and biochemical signaling pathways altered by RECK, a major metastasis suppressor gene in breast cancer. We overexpressed RECK in 2 highly invasive cell lines and knocked-down RECK expression in ...
ORGANISM(S): Homo sapiens 
2014-09-01 | GSE56898 | GEO
TranscriptomicsRNA-seq analysis of WT vs. Reck vascular KO P0 mouse brains
We examined, compared, and analyzed the transcriptome profile (RNA-seq) of WT vs Reck vascular KO (Reck flex2/Δex1; Tie2Cre) P0 mouse brains. Specifically, cortical transcriptomic differences (between WT and mutant genotypes) were compared separately from subcortical transcriptomic changes.
ORGANISM(S): Mus musculus 
2017-08-10 | GSE94814 | GEO
TranscriptomicsRECK Controls Breast Cancer Metastasis by Modulating a Convergent, STAT3-dependent Neoangiogenic Switch
Metastasis leads to the majority of deaths in breast cancer patients. Here we investigated the molecular and biochemical signaling pathways altered by RECK, a major metastasis suppressor gene in breast cancer. We overexpressed RECK in 2 highly invasive cell lines and knocked-down RECK expression in...
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-56898 | biostudies-arrayexpress
UnknownRECK isoforms have opposing effects on cell migration.
Not available
S-EPMC6085827 | biostudies-literature
GenomicsMus musculus
RNA sequencing of three Reck-null-PDAC cell lines with ether a control vector or RECK-expression vector
PRJDB13083 | ENA
GenomicsHomo sapiens
Expression data from RECK-overexpressing HT1080 fibrosarcoma cells
PRJNA126575 | ENA
UnknownThe RECK tumor-suppressor protein binds and stabilizes ADAMTS10.
Not available
S-EPMC6215420 | biostudies-literature
UnknownLow RECK Expression Is Part of the Cervical Carcinogenesis Mechanisms.
Not available
S-EPMC8124470 | biostudies-literature
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