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8-oxo-7,8-dihydroguanine (8-oxoG) is a common RNA oxidation that has been implicated in carcinogenesis, neurodegeneration, and aging. Some? Many? RNA-binding proteins have shown binding preference for 8-oxoG modified RNA; such binding? can protect cells from oxidative stress. To date, the presence o...
ORGANISM(S): Deinococcus radiodurans ATCC 13939 
2022-07-09 | PXD028866 | Pride
WT, ∆rhlB and ∆rppH mRNA half-life profiling.
WT, ∆rhlB and ∆rppH strains were globally profiled for mRNA half-lives using rifampicin treatment followed by RNA-seq. Wild type(WT) was compared to ∆rhlB (deleted RNA helicase RhlB gene) and ∆rppH (deleted RppH gene) strains
ORGANISM(S): Caulobacter vibrioides 
2023-04-03 | GSE228592 | GEO
PNPase, one of the major enzymes with 3ʹ-to-5ʹ single-stranded RNA (ssRNA) degradation and processing activities, can interact with the RNA helicase RhlB independent of RNA degradosome formation in E. coli. Here we report that loss of interaction between RhlB and PNPase impacts cysteine homeostasis ...
ORGANISM(S): Escherichia coli 
2015-11-10 | GSE57784 | GEO
8-oxo-7,8-dihydroguanine (8-oxoG) is a common RNA oxidation that has been implicated in carcinogenesis, neurodegeneration, and aging. Some? Many? RNA-binding proteins have shown binding preference for 8-oxoG modified RNA; such binding? can protect cells from oxidative stress. To date, the presence o...
ORGANISM(S): Deinococcus radiodurans ATCC 13939 
2022-07-10 | PXD028861 | Pride
Genomics
Impact of RhlB helicase on Caulobacter crescentus transcriptome
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