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G-patch proteins are emerging as key regulatory cofactors of DEAH-box RNA helicases involved in pre-mRNA splicing, yet the functions of many family members remain poorly understood. Here, we characterize the conserved G-patch domain–containing protein Cwf28 from Schizosaccharomyces pombe, an essenti...
ORGANISM(S): Schizosaccharomyces pombe 
2026-08-24 | PXD080271 | Pride
The essential process of pre-mRNA splicing must occur with high fidelity and efficiency for proper gene expression. The spliceosome employs DExD/H box helicases to promote on-pathway interactions while simultaneously minimizing errors. Prp8 and Snu114, an EF2-like GTPase, regulate the activity of th...
ORGANISM(S): Saccharomyces cerevisiae 
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