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ProteomicsTMT-based proteomics analysis identifies RPLP1 as a key protein target in ursolic acid inhibition of colorectal cancer
Purpose: Ursolic Acid (UA), a triterpenoid extracted from Hedyotis Diffusa Willd. (HDW), is known for its anti-inflammatory, antioxidant, and antitumor effects. Nevertheless, the mechanisms underlying UA's anti-colorectal cancer (CRC) effects remain insufficiently understood. This study is aim to id...
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD063684 | Pride
Colorectal cancer  hedyotis diffusa willd  ursolic acid  rplp1  tandem mass tags 
TranscriptomicsRibosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV.
We used ribosome profiling to evaluate viral and cellular translation in RPLP1/2-depleted cells. This revealed that ribosomes pause in the sequence coding for the N-terminus of the envelope protein, immediately downstream of sequences encoding two adjacent transmembrane domains (TMDs). RPLP1/2 funct...
ORGANISM(S): Homo sapiens 
2019-06-21 | GSE133111 | GEO
GenomicsRibosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV.
Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV.
PRJNA549955 | ENA
UnknownUnveiling the prognostic implications of RPLP1 upregulation in osteosarcoma.
Not available
S-EPMC10636679 | biostudies-literature
UnknownRPLP1, a crucial ribosomal protein for embryonic development of the nervous system.
Not available
S-EPMC4069005 | biostudies-literature
UnknownRPLP1 restricts HIV-1 transcription by disrupting C/EBPβ binding to the LTR.
Not available
S-EPMC11192919 | biostudies-literature
UnknownRPLP1, an NS4B-interacting protein, enhances production of CSFV through promoting translation of viral genome.
Not available
S-EPMC8824197 | biostudies-literature
UnknownRibosomal stalk proteins RPLP1 and RPLP2 promote biogenesis of flaviviral and cellular multi-pass transmembrane proteins.
Not available
S-EPMC7515724 | biostudies-literature
UnknownExploring the function and prognostic value of RPLP0, RPLP1 and RPLP2 expression in lung adenocarcinoma.
Not available
S-EPMC11567986 | biostudies-literature
UnknowncDNA cloning and overexpression of acidic ribosomal phosphoprotein P1 gene (RPLP1) from the giant panda.
Not available
S-EPMC2043164 | biostudies-literature
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