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ProteomicsInteractome of Sec13 paralogs in Paradiplonema papillatum
The acquisition of new functions is frequently the result of gene duplication and is a major driver of evolutionary complexity. The β-propeller protein Sec13 plays roles in at least three distinct processes by virtue of being a component of the COPII endoplasmic reticulum export vesicle coat, the n...
ORGANISM(S): Diplonema papillatum 
2023-06-14 | PXD037122 | Pride
Paralog expansion Diplonema  coatomer  membrane-trafficking  sec13  nuclear pore complex (npc)  sea/gator complex Evolutionary mechanisms 
TranscriptomicsSEC13 functions in the NMD pathway and together with core NMD factors regulates the unfolded protein response
The nonsense-mediated decay pathway (NMD) is an RNA quality control mechanism that regulates the stability of target RNAs. We previously identified SEC13 (nuclear pore and COPII coat complex component), as a novel NMD factor in C. elegans and in HeLa cells; however, its mechanistic role in the NMD p...
ORGANISM(S): Homo sapiens 
2026-05-06 | GSE329468 | GEO
GenomicsSEC13 functions in the NMD pathway and together with core NMD factors regulates the unfolded protein response
SEC13 functions in the NMD pathway and together with core NMD factors regulates the unfolded protein response
PRJNA1459306 | ENA
UnknownFunctional differentiation of Sec13 paralogues in the euglenozoan protists.
Not available
S-EPMC10264103 | biostudies-literature
UnknownSec13 Regulates Expression of Specific Immune Factors Involved in Inflammation In Vivo.
Not available
S-EPMC4668385 | biostudies-literature
UnknownSec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.
Not available
S-EPMC8970680 | biostudies-literature
UnknownEarly stages of retinal development depend on Sec13 function.
Not available
S-EPMC3603407 | biostudies-literature
UnknownEpithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion.
Not available
S-EPMC3367830 | biostudies-literature
UnknownGenetic marker identification of SEC13 gene for milk production traits in Chinese holstein.
Not available
S-EPMC9846039 | biostudies-literature
UnknownStructure of the Sec13-Sec16 edge element, a template for assembly of the COPII vesicle coat.
Not available
S-EPMC2922654 | biostudies-literature
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