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GenomicsNEXN protects against vascular calcification by promoting SERCA2 SUMOy-lation and stabilization
NEXN protects against vascular calcification by promoting SERCA2 SUMOy-lation and stabilization
PRJNA1265212 | ENA
TranscriptomicsNEXN protects against vascular calcification by promoting SERCA2 SUMOy-lation and stabilization
Vascular calcification, a key risk factor for cardiovascular diseases, is driven by the phenotypic transition of vascular smooth muscle cells (VSMCs) from a contractile to an osteogenic phenotype. NEXN, a protein highly associated with heart function, has also been implicated as a potential suscepti...
ORGANISM(S): Homo sapiens 
2025-06-04 | GSE297578 | GEO
TranscriptomicsATP2A2 and miRNA in human myocardial infarction
Cardiac sarco(endo)plasmic reticulum calcium ATPase-2 (SERCA2) plays one of the central roles in myocardial contractility. Both, SERCA2 mRNA and protein are reduced in myocardial infarction (MI), but the correlation has not been always observed. MicroRNAs (miRNAs) act by targeting 3'-UTR mRNA, causi...
ORGANISM(S): Homo sapiens 
2012-04-29 | E-GEOD-17304 | biostudies-arrayexpress
UnknownFar-infrared irradiation attenuates vessel contraction by activating SERCA2 through disruption of SERCA2 and PLN interaction.
Not available
S-EPMC12711061 | biostudies-literature
UnknownCharacterization of calumenin-SERCA2 interaction in mouse cardiac sarcoplasmic reticulum.
Not available
S-EPMC2781510 | biostudies-literature
UnknownPolyarginine Cell-Penetrating Peptides Bind and Inhibit SERCA2.
Not available
S-EPMC10571751 | biostudies-literature
UnknownRole of TG2-Mediated SERCA2 Serotonylation on Hypoxic Pulmonary Vein Remodeling.
Not available
S-EPMC7026497 | biostudies-literature
GenomicsPancreatic β cell SERCA2 deficiency leads to impaired proinsulin processing and reduced ER to Golgi protein trafficking
Pancreatic β cell SERCA2 deficiency leads to impaired proinsulin processing and reduced ER to Golgi protein trafficking
PRJNA855926 | ENA
UnknownSERCA2 regulates non-CF and CF airway epithelial cell response to ozone.
Not available
S-EPMC3214057 | biostudies-literature
UnknownSilencing calcineurin A subunit reduces SERCA2 expression in cardiac myocytes.
Not available
S-EPMC3023267 | biostudies-literature
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