site-specific recombination

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Chromosome dynamics and genome stability, Institute of Epigenetics and Stem Cells, Helmholtz Zentrum München, Feodor-Lynen-Strasse 21, 81377 München, Germany (1)
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Institute of Epigenetics and Stem Cells, Helmholtz ZentrumMünchen, Feodor-Lynen- Strasse 21, 81377 München, Germany (1)
Medical Bioanalytics Institute for Ophthalmic Research Eberhard-Karls University of Tuebingen Elfriede-Aulhorn-Str. 5-7 D-72076 Tübingen (1)
Medical University of Vienna (1)
Novo Nordisk Foundation Center for Protein Research, Proteomics program, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (1)
Proteome Exploration Laboratory (1)

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Zinc finger DNA-binding conditioned site-specific recombination

PRJNA1019370 | ENA

Supression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic spo11 allele

Homologous recombination is the key process that generates genetic diversity and drives evolution. SPO11 protein triggers recombination by introducing DNA double stranded breaks at discreet areas of the genome called recombination hotspots. The hotspot locations are largely determined by the DNA bin...

ORGANISM(S): Mus musculus

2013-09-11 | E-GEOD-48493 | biostudies-arrayexpress

Characterization of attB and core-attP recombination sites of the integrase from Lactobacilus delbrueckii subsp. bulgaricus bacteriophage mv4

Different attB or attP DNA libraries containing 7-bp random nucleotides were used for in vitro recombination mediated by the purified integrase from mv4 bacteriophage against their cognate wild-type attB or attP recombination site.

ORGANISM(S): Lactobacillus delbrueckii subsp. bulgaricus

2023-12-10 | E-MTAB-13571 | biostudies-arrayexpress

Meiotic recombination cold spots in chromosomal cohesion sites [ChIP-Seq]

Meiotic chromosome architecture called M-bM-^@M-^\axis-loop structuresM-bM-^@M-^] and histone modifications have been demonstrated to regulate the Spo11-dependent formation of DNA double-strand breaks (DSBs) that trigger meiotic recombination. Using genome-wide chromatin immunoprecipitation (ChIP) a...

ORGANISM(S): Saccharomyces cerevisiae

2014-03-31 | E-GEOD-52862 | biostudies-arrayexpress

The DSIF subunits Spt4 and Spt5 have several unexpected, distinct roles in regulating immunoglobulin class switch recombination

Class-switch recombination (CSR), induced by activation-induced cytidine deaminase, can be divided into two phases: DNA cleavage of the switch (S) regions, and the joining of the cleaved ends of the different S regions. Here, we show that the DSIF complex (Spt4 and Spt5), a transcription elongation ...

ORGANISM(S): Mus musculus

2013-10-22 | E-GEOD-33206 | biostudies-arrayexpress

Artificial nondirectional site-specific recombination systems.

Not available

S-EPMC8762395 | biostudies-literature

phiC31 integrase-mediated site-specific recombination in barley.

Not available

S-EPMC3443236 | biostudies-literature

Site-specific recombination system encoded by toluene catabolic transposon Tn4651.

Not available

S-EPMC135285 | biostudies-literature

The λ Integrase Site-specific Recombination Pathway.