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MetabolomicsEarly-life skin molecular signatures are predictive of atopic dermatitis risk in an Asian preconception birth cohort
Rationale: Early identification of infants at risk for atopic dermatitis (AD) is critical for timely prevention, yet robust preclinical biomarkers remain elusive. We characterized the longitudinal evolution of the skin microbiome, metabolome, and proteome to identify molecular signatures predictive ...
2026-10-05 | MTBLS14496 | MetaboLights
MetabolomicsDecipher aging related skin microbiome and metabolites crosstalk from a chronologically matched cohort

Aging has shown close link to shifts in the skin microbiome in population cohort study. However, how variations in microbial communities relate to divergent skin aging within individuals of the same chronological ages remains unclear. In this study, we performed phenotypic, metabolomic and metage...

2025-01-03 | MTBLS11994 | MetaboLights
MetabolomicsGut microbiota-induced perturbations in bile acids alter keratinocyte lipid metabolism via FXR-NQO1 signaling in psoriasis
Emerging evidence has shown that microbiota dysbiosis and aberrant bile acids (BAs) profiles are correlated with disease progression. This study elucidates dysregulated BAs metabolism in psoriasis patients and imiquimod-treated female mice, coupled with increased expression of the farnesoid X recept...
2026-03-31 | MTBLS14191 | MetaboLights
Genomicsskin metagenome
Skin microbiota
PRJNA946350 | ENA
ProteomicsGut commensal bacteria Parabacteroides goldsteinii JCM 13446 derived-outer membrane vesicles suppress skin inflammation in psoriasis
Proteomic analysis of outer membrane vesicles derived from Parabacteroides goldsteinii JCM 13446
ORGANISM(S): Parabacteroides Goldsteinii Dsm 19448 = Wal 12034 
PXD056885 |
Genomicsskin metagenome
Skin microbiota (PRJCA041575)
PRJDB37113 | ENA
Genomicshuman skin metagenome
Human skin microbiota pilot 2
PRJNA30125 | ENA
Genomicsfish skin mucosal microbiota
fish skin mucosal microbiota Raw sequence reads
PRJNA792590 | ENA
Genomicsmouse skin metagenome
Mouse skin microbiota pilot 1
PRJNA30121 | ENA
Genomicsskin metagenome
Pig skin microbiota Metagenome
PRJNA231552 | ENA
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