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MetabolomicsSpirulina Prevents Hepatic Steatosis by Promoting Macrophage M2 Polarization via Gut Microbiota-Derived 2-Hydroxy-3-Methylbutyrate

Background & Aims:

Spirulina, a microalgae renowned for its nutrient density, shows promise in modulating glucose and lipid metabolism. However, its efficacy and underlying mechanisms against metabolic dysfunction-associated steatotic liver disease (MASLD) remain unclear. We hypothesize...

2026-01-11 | MTBLS13653 | MetaboLights
MetabolomicsSpirulina Prevents Hepatic Steatosis by Promoting Macrophage M2 Polarization via Gut Microbiota-Derived 2-Hydroxy-3-Methylbutyrate

Background & Aims:

Spirulina, a microalgae renowned for its nutrient density, shows promise in modulating glucose and lipid metabolism. However, its efficacy and underlying mechanisms against metabolic dysfunction-associated steatotic liver disease (MASLD) remain unclear. We hypothesize...

2026-01-12 | MTBLS13657 | MetaboLights
MetabolomicsSpirulina Alleviates Functional Constipation by Remodeling Gut Microbiota and Fecal Metabolites: A Metagenomic and Metabolomic Study
Abstract Objective: Functional constipation (FC) is a common gastrointestinal disorder that significantly affects quality of life. Increasing evidence suggests that gut microbiota and their derived metabolites play a critical role in FC, yet the therapeutic potential of Spirulina and its underlying ...
2026-09-30 | MTBLS15871 | MetaboLights
MetabolomicsSpirulina Prevents Hepatic Steatosis by Promoting Macrophage M2 Polarization via Gut Microbiota-Derived 2-Hydroxy-3-Methylbutyrate
Background & Aims: Spirulina, a microalgae renowned for its nutrient density, shows promise in modulating glucose and lipid metabolism. However, its efficacy and underlying mechanisms against metabolic dysfunction-associated steatotic liver disease (MASLD) remain unclear. We hypothesized that spirul...
2026-06-30 | MTBLS14901 | MetaboLights
MetabolomicsSpirulina Prevents Hepatic Steatosis by Promoting Macrophage M2 Polarization via Gut Microbiota-Derived 2-Hydroxy-3-Methylbutyrate
Background & Aims: Spirulina, a microalgae renowned for its nutrient density, shows promise in modulating glucose and lipid metabolism. However, its efficacy and underlying mechanisms against metabolic dysfunction-associated steatotic liver disease (MASLD) remain unclear. We hypothesized that spirul...
2026-06-30 | MTBLS14903 | MetaboLights
ProteomicsTMT-based proteomics of longissimus lumborum muscle in newly weaned piglets after dietary Spirulina inclusion and enzyme supplementation
The objective of this study was to evaluate the impact of dietary Spirulina and lysozyme supplementation over the muscle proteome of piglets during the post-weaning stage. Thirty piglets were randomly distributed among three diets: control (no microalga), SP (10% Spirulina) and SP+L (10% Spirulina +...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-05-24 | PXD024083 | Pride
Spirulina Weaned piglet Muscle proteome Tandem mass tag Cazyme 
GenomicsSpirulina subsalsa FACHB-351
Spirulina subsalsa FACHB-351 Genome sequencing and assembly
PRJNA753976 | ENA
GenomicsSpirulina bacteria
Spirulina bacteria Metagenome
PRJNA926888 | ENA
GenomicsBacteria associated with Spirulina biomass during the biogas producation
Bacteria associated with Spirulina biomass during the biogas producation Metagenomic assembly
PRJNA822084 | ENA
GenomicsSpirulina subsalsa
Spirulina subsalsa overview
PRJNA879841 | ENA
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