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TranscriptomicsOverexpression of splicing factor SRSF6 in mouse skin
Many biological processes involve post-transcriptional regulation of gene expression by alternative pre-mRNA splicing. Here, we show that an alternative splicing factor SRSF6 affects tissue homeostasis of the skin. In this dataset, we study effects on gene expression and alternative splicing upon SR...
ORGANISM(S): Mus musculus 
2014-01-19 | E-GEOD-52458 | biostudies-arrayexpress
TranscriptomicsOverexpression of splicing factor SRSF6 in mouse skin
Many biological processes involve post-transcriptional regulation of gene expression by alternative pre-mRNA splicing. Here, we show that an alternative splicing factor SRSF6 affects tissue homeostasis of the skin. In this dataset, we study effects on gene expression and alternative splicing upon SR...
ORGANISM(S): Mus musculus 
2014-01-19 | GSE52458 | GEO
UnknownSplicing factor SRSF6 mediates pleural fibrosis.
Not available
S-EPMC8262297 | biostudies-literature
TranscriptomicsIdentification of SRSF6 downstream regulatory genes and its impact on pleural fibrosis progression
Pleural fibrosis is defined as an excessive deposition of extracellular matrix that results in destruction of the normal pleural tissue architecture and compromised function. There is no effective medication for this disorder. Pleural mesothelial cells (PMCs/ Met-5A) play a key role in the process o...
ORGANISM(S): Homo sapiens 
2021-03-30 | GSE168578 | GEO
UnknownTargeting Splicing Factor SRSF6 for Cancer Therapy.
Not available
S-EPMC8669609 | biostudies-literature
TranscriptomicsSRSF6 -regulated alternative splicing of genes involved in DNA repair is associated with prostate cancer progression 
Alternative splicing (AS) occurs in nearly all human genes and abnormal AS has a close connection with cancer. SRSF6, a canonical member of the serine/arginine-rich (SR) protein family, has been characterized as an important regulator of AS. However, the role of SRSF6 in regulating AS in prostate ca...
ORGANISM(S): Homo sapiens 
2020-10-20 | GSE138636 | GEO
GenomicsIdentification of SRSF6 splicing regulatory map and its impact on diabetes susceptibility genes regulation
Identification of SRSF6 splicing regulatory map and its impact on diabetes susceptibility genes regulation
PRJNA631368 | ENA
GenomicsSRSF6 -regulated alternative splicing of genes involved in DNA repair is associated with prostate cancer progression
SRSF6 -regulated alternative splicing of genes involved in DNA repair is associated with prostate cancer progression
PRJNA576647 | ENA
UnknownSplicing factor SRSF6 promotes hyperplasia of sensitized skin.
Not available
S-EPMC4118672 | biostudies-literature
GenomicsRNA-seq of HeLa cells stably overexpressing SRSF6-GFP grown under normoxic and hypoxic conditions
RNA-seq of HeLa cells stably overexpressing SRSF6-GFP grown under normoxic and hypoxic conditions
PRJNA814541 | ENA
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