steroidal alkaloid

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Unknown (69)
Genomics (7)
Transcriptomics (5)
Metabolomics (5)
Proteomics (2)

Organisms

Homo sapiens (2)
Alphavirus (2)
Anemia (2)
Archaea (2)
Bacteria (2)
Betaherpesvirinae (2)
Borrelia (2)
Chlamydomonas reinhardtii (2)
Chlorella vulgaris (2)
Clostridium perfringens (2)
Dengue virus (2)
Eukaryota (2)
Hepatitis B virus (2)
Human alphaherpesvirus 1 (2)
Human betaherpesvirus 5 (2)
Influenza A virus (2)
Influenza C virus (2)
Japanese encephalitis virus group (2)
Kamptonema sp. (2)
Listeria monocytogenes (2)
Mammarenavirus (2)
Miscanthus x giganteus (2)
Mycobacterium tuberculosis (2)
Orthoflavivirus (2)
Pseudomonas aeruginosa (2)
Rattus (2)
Sarbecovirus (2)
Severe acute respiratory syndrome coronavirus 2 (2)
Saccharomyces cerevisiae (1)
Salamandra salamandra (1)

Organisms

Homo sapiens (2)
Salamandra salamandra (1)
Veratrum grandiflorum (1)

Repository

ENA (7)
MetaboLights (5)
geo (3)
biostudies-arrayexpress (2)
pride (2)

Tissue

Cell culture (1)
Hepatocyte (1)

Disease

Disease free (1)

Technology Type

Mass spectrometry (5)
Mass Spectrometry (2)
Bottom-up proteomics (1)
Data-independent acquisition (1)
Gel-based experiment (1)

Instrument Platform

Liquid Chromatography MS - positive - reverse phase (3)
6550 Q-TOF LC-MS Agilent (1)
Liquid Chromatography MS - Negative (LC-MS (Negative)) (1)
Liquid Chromatography MS - Positive (LC-MS (Positive)) (1)
Liquid Chromatography MS - negative - reverse phase (1)

Publication Date

2025 (3)
2018 (2)
2023 (2)
2011 (1)
2007 (1)
2017 (1)
2019 (1)
2021 (1)

CHEBI ID

CHEBI:6650 (2)
CHEBI:139429 (1)
CHEBI:139434 (1)
CHEBI:139451 (1)
CHEBI:139435 (1)
CHEBI:139448 (1)
CHEBI:139460 (1)
CHEBI:139442 (1)
CHEBI:139410 (1)
CHEBI:139428 (1)
CHEBI:139404 (1)
CHEBI:139422 (1)
CHEBI:139425 (1)
CHEBI:139440 (1)
CHEBI:139432 (1)
CHEBI:139450 (1)
CHEBI:139439 (1)
CHEBI:139456 (1)
CHEBI:94167 (1)
CHEBI:139407 (1)
CHEBI:139423 (1)
CHEBI:139459 (1)
CHEBI:139403 (1)
CHEBI:139437 (1)
CHEBI:139405 (1)
CHEBI:139414 (1)
CHEBI:139470 (1)
CHEBI:139402 (1)
CHEBI:139433 (1)
CHEBI:139409 (1)

Metabolite Name

4-O-trans-caffeoylquinic acid (1)
2-hydroxy-2-(4-hydroxybenzyl)succinic acid (1)
(3R,5R)-3,4,5-tris{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1-hydroxycyclohexane-1-carboxylic acid (1)
3-(4-hydroxyphenyl)-1-{2,4,6-trihydroxy-3,5-bis(2S,3R,4R,5S,6R)[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl}propan-1-one (1)
(1S,3S,4R,5R)-3-{[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]oxy}-1,4,5-trihydroxycyclohexanecarboxylic acid (1)
(3E)-1-hydroxy-4-[(1R)-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl]-3-buten-2-yl beta-D-glucopyranoside (1)
(2E)-3-[4-(beta-D-Glucopyranosyloxy)-3-methoxyphenyl]acrylic acid (1)
(2E)-N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(3,4-dimethoxyphenyl)acrylamide (1)
(3R)-3,7-dimethyl-1,6-octadien-3-yl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside (1)
{2-[5-(hexopyranosyloxy)pent-2-en-1-yl]-3-oxocyclopentyl}acetic acid (1)
5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-3-yl 6-O-(6-deoxyhexopyranosyl)hexopyranoside (1)
8-[6-(3-{[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy}-5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2,3-dihydroxyphenyl]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside (1)
Kaempferol 3-O-beta-D-galactoside (1)
Kaempferol 3-O-beta-D-glucoside (1)
2,6-dihydroxy-2-[(4-hydroxyphenyl)methyl]-3-oxo-2,3-dihydro-1-benzofuran-4-yl hexopyranoside (1)
5-{4-[4-(hexopyranosyloxy)-3,5-dimethoxyphenyl]tetrahydro-1H,3H-furo[3,4-c]furan-1-yl}-2-methoxyphenyl hexopyranoside (1)
[4-(4-hydroxy-3-methoxybenzyl)-2-(4-hydroxy-3-methoxyphenyl)tetrahydro-3-furanyl]methyl hexopyranoside (1)
4-[4-(4-hydroxy-3-methoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl hexopyranoside (1)
Glycosyldiacylglycerols (1)
3-O-alpha-L-Arabinopyranosylproanthocyanidin A5' (1)
Sulfoquinovosyldiacylglycerols (1)
Triterpene saponins (1)
Ketals (1)
Peonidin 3-(4-sinapoylgentiobioside) (1)
Dialkylglycerophosphoethanolamines (1)
I(3)-Tocotrienol (1)
Sapimukoside J (1)
2,3-dihydroxypropyl icos-11-enoate (1)
17-(7-hydroxy-6-methylhept-5-en-2-yl)-4,4,10,13,14-pentamethyl-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one (1)
2,2,3-Trimethyltridecanoic acid (1)

First Public Date

2025 (3)
2024 (1)
2023 (1)
2018 (1)
2017 (1)

Study type

Transcription profiling by array (2)

Release Date

2023 (12)
2025 (10)
2022 (8)
2024 (7)
2021 (5)
2020 (5)
2018 (5)
2011 (3)
2019 (3)
2016 (3)
2013 (2)
2012 (2)
2007 (1)
2017 (1)
2015 (1)
2008 (1)
2004 (1)
2002 (1)

Lab affiliation

Department of Medical Microbiology and Infection Prevention, University of Groningen; University Medical Center Groningen; Groningen, the Netherlands (1)
Staff Scientist Biological Systems & Engineering Division Lawrence Berkeley National Laboratory Berkeley CA 94720 (1)

Tags

xref:PubMed:29504232 (1)
xref:PubMed:41059198 (1)
xref:PubMed:28604738 (1)

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Transcriptomics and Metabolomics Reveal Alterations in Xenobiotic Metabolism and Appearance of Steroidal Alkaloid Metabolites in Mouse Livers after Tomato Consumption

SCOPE: Tomato consumption is associated with many health benefits including lowered risk for developing certain cancers. It is hypothesized that tomato phytochemicals are transported to the liver and other tissues where they alter gene expression in ways that lead to favorable he...

2023-06-13 | MTBLS6715 | MetaboLights

Verazine Biosynthesis from Simple Sugars in Engineered Saccharomyces cerevisiae

Steroidal alkaloids are FDA-approved drugs (e.g., Zytiga) and promising drug candidates/leads (e.g., cyclopamine); yet many of the ≥ 697 known steroidal alkaloid natural products remain underutilized as drugs because it can be challenging to scale their biosynthesis in their producing organisms. Cyc...

ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast)

2025-03-08 | PXD053024 | Pride

High-Throughput Detection of an Alkaloidal Plant Metabolome in Plant Extracts Using LC-ESI-QTOF-MS.

Plant alkaloids represent a diverse group of nitrogen-containing natural products. These compounds are considered valuable in drug discovery and development. High-throughput identification of such plant secondary metabolites in complex plant extracts is essential for drug discovery, lead optimizatio...

2023-12-12 | MTBLS2914 | MetaboLights

Plakinamine M, a steroidal alkaloid from the marine sponge Corticium sp.

Not available

S-EPMC3883566 | biostudies-literature

Comparative transcriptome analysis of Veratrum maackii and Veratrum nigrum reveals multiple candidate genes involved in steroidal alkaloid biosynthesis.

Not available

S-EPMC10200796 | biostudies-literature

Plakinamine P, A Steroidal Alkaloid with Bactericidal Activity against Mycobacterium tuberculosis.

Not available

S-EPMC6950683 | biostudies-literature

Transcriptome analysis reveals in vitro-cultured regeneration bulbs as a promising source for targeted Fritillaria cirrhosa steroidal alkaloid biosynthesis.

Not available