subtherapeutic-dose of ionizing radiation - OmicsDI

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Subtherapeutic-Dose of Ionizing Radiation Reprograms the Pre-Metastatic Lung Niche, Accelerating Its Formation and Promoting Metastasis

Pre-metastatic niche (PMN) formation is a critical step in metastatic progression, yet the biological effect of subtherapeutic-dose of ionizing radiation (SDIR) following radiotherapy on this process remains unclear. Using a 4T1 breast cancer mouse model, we investigated the effects of SDIR (3×0.3 G...

ORGANISM(S): Mus musculus (Mouse)

2025-07-21 | PXD062108 | Pride

Pre-metastatic niche subtherapeutic-dose of ionizing radiation metastasis

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