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GenomicsSulfonylurea receptor 1 deficiency alleviates acute lung injury by activating PARP1 in epithelial cells
Sulfonylurea receptor 1 deficiency alleviates acute lung injury by activating PARP1 in epithelial cells
PRJNA1518842 | ENA
UnknownSulfonylurea receptor 1 expression in human cerebral infarcts.
Not available
S-EPMC3771575 | biostudies-literature
TranscriptomicsSulfonylurea receptor 1 deficiency alleviates acute lung injury by activating PARP1 in epithelial cells
Acute lung injury (ALI) is a critical disease with high mortality, yet its mechanisms remain incompletely elucidated. In this study we investigated sulfonylurea receptor 1 (SUR1), the regulatory subunit of ATP-sensitive potassium (KATP) channels, in the progression of ALI. We observed elevated SUR1 ...
ORGANISM(S): Homo sapiens 
2026-08-26 | GSE345117 | GEO
UnknownEffective treatment with oral sulfonylureas in patients with diabetes due to sulfonylurea receptor 1 (SUR1) mutations.
Not available
S-EPMC7611807 | biostudies-literature
UnknownSulfonylurea receptor 1 in central nervous system injury: a focused review.
Not available
S-EPMC3434627 | biostudies-literature
ProteomicsMechanism of pharmacochaperoning in ATP-sensitive potassium channels revealed by cryo-EM
ATP-sensitive potassium (K-ATP) channels composed of a pore-forming Kir6.2 potassium channel and a regulatory ABC transporter sulfonylurea receptor 1 (SUR1) regulate insulin secretion in pancreatic beta-cells to maintain glucose homeostasis. Mutations that impair channel folding or assembly prevent ...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-11-12 | PXD013873 | Pride
Pharmacological chaperones  sulfonylureas  glinides  carbamazepine  sulfonylurea receptor 1  kir6.2  structure 
ProteomicsMechanism of pharmacochaperoning in ATP-sensitive potassium channels revealed by cryo-EM
ATP-sensitive potassium (K-ATP) channels composed of a pore-forming Kir6.2 potassium channel and a regulatory ABC transporter sulfonylurea receptor 1 (SUR1) regulate insulin secretion in pancreatic beta-cells to maintain glucose homeostasis. Mutations that impair channel folding or assembly prevent ...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-08-12 | PXD014498 | Pride
Pharmacological chaperones  sulfonylureas  glinides  carbamazepine  sulfonylurea receptor 1  kir6.2  structure 
UnknownRole of Sulfonylurea Receptor 1 and Glibenclamide in Traumatic Brain Injury: A Review of the Evidence.
Not available
S-EPMC7013742 | biostudies-literature
UnknownMice transgenically overexpressing sulfonylurea receptor 1 in forebrain resist seizure induction and excitotoxic neuron death.
Not available
S-EPMC30690 | biostudies-literature
UnknownA role of the sulfonylurea receptor 1 in endocytic trafficking of ATP-sensitive potassium channels.
Not available
S-EPMC3155645 | biostudies-literature
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