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Methylation profilingDNA methylation profiling identifies TBKBP1 as potent amplifier of cytotoxic activity in CMV-specific human CD8+ T cells
Epigenetic mechanisms stabilize gene expression patterns during CD8+ T cell differentiation. Although adoptive transfer of virus-specific T cells is clinically applied to reduce the risk of virus infection or reactivation in immunocompromised individuals, the DNA methylation pattern of virus-specifi...
ORGANISM(S): Homo sapiens 
2024-09-12 | GSE245832 | GEO
GenomicsDNA methylation profiling identifies TBKBP1 as potent amplifier of cytotoxic activity in CMV-specific human CD8+ T cells
DNA methylation profiling identifies TBKBP1 as potent amplifier of cytotoxic activity in CMV-specific human CD8+ T cells
PRJNA1030038 | ENA
UnknownDNA methylation profiling identifies TBKBP1 as potent amplifier of cytotoxic activity in CMV-specific human CD8+ T cells.
Not available
S-EPMC11460711 | biostudies-literature
UnknownTBKBP1 induces capecitabine resistance through negative regulation of type I interferon pathway in triple-negative breast cancer.
Not available
S-EPMC12867762 | biostudies-literature
UnknownAnalysis of PPARGC1B, RUNX3 and TBKBP1 polymorphisms in Chinese Han patients with ankylosing spondylitis: a case-control study.
Not available
S-EPMC3630117 | biostudies-literature
UnknownA multi-step genomic approach prioritized TBKBP1 gene as relevant for multiple sclerosis susceptibility.
Not available
S-EPMC9294010 | biostudies-literature
UnknownTBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival.
Not available
S-EPMC6052109 | biostudies-literature
ProteomicsMolluscum Contagiosum Virus Protein MC089 Inhibits Interferon Regulatory Factor 3 Activation
Molluscum contagiosum virus (MCV) is a human-specific poxvirus that causes a highly common but mild infection characterised by distinctive and persistent papular skin lesions. These lesions can persist for long periods without an effective clearance response from the host. MCV, like all poxviruses, ...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD054178 | Pride
Molluscum contagiosum virus  mc089  innate immunity  ikkε  tbkbp1  nap1  mavs. 
UnknownTBK1 adaptor AZI2/NAP1 regulates NDP52-driven mitochondrial autophagy.
Not available
S-EPMC11490886 | biostudies-literature
UnknownInteraction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility.
Not available
S-EPMC3640413 | biostudies-literature
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