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Understanding the genomic toolkit that enabled animal terrestrialization, the shift from aquatic to terrestrial habitats, is key to uncovering the evolutionary origins of land biodiversity. Yet, the genomic basis of the physiological and metabolic adaptations required for life on land remains poorly...
ORGANISM(S): Obama nungara Schmidtea mediterranea (Freshwater planarian flatworm) 
2026-04-06 | PXD074775 | Pride
Animal mucosal barriers constantly interact with the external environment and this interaction is markedly different in aquatic and terrestrial environments. Transitioning from water to land was a critical step in vertebrate evolution but the immune adaptations that mucosal barriers such as the skin...
ORGANISM(S): Protopterus dolloi 
2018-10-19 | PXD008981 | Pride
Animal mucosal barriers constantly interact with the external environment and this interaction is markedly different in aquatic and terrestrial environments. Transitioning from water to land was a critical step in vertebrate evolution but the immune adaptations that mucosal barriers such as the skin...
ORGANISM(S): Protopterus dolloi 
2018-10-19 | PXD008982 | Pride
A single-cell atlas of West African lungfish respiratory system reveals evolutionary adaptations to terrestrialization
The six species of lungfish possess both lungs and gills and are the closest extant relatives of tetrapods. Here, we report a single-cell transcriptome atlas of the West African lungfish (Protopterus annectens). This species manifests the most extreme form of terrestrialization, a life history strat...
ORGANISM(S): Protopterus annectens 
2023-08-05 | GSE240094 | GEO
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