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ProteomicsDiscovery of a testis-specific complex TEX101-DPEP3 and selection of its disrupting antibodies
TEX101 is a testis-specific protein expressed exclusively in male germ cells and is a validated biomarker of male infertility. Studies in mice suggest that TEX101 is a cell-surface chaperone which regulates, through protein-protein interactions, the maturation of proteins involved in spermatozoa tra...
ORGANISM(S): Homo sapiens (Human) 
2018-08-16 | PXD007515 | Pride
Tex101  testis-expressed sequence 101 protein  dpep3  dipeptidase 3  affinity purification-mass spectrometry  interactome  protein-protein interactions  testis-specific proteins  spermatozoa  disrupting antibodies 
ProteomicsIdentification of a damaging variant rs35033974 associated with idiopathic male infertility through degradation of TEX101 protein and its transient interactome
Human TEX101 is a testis-specific cell membrane protein expressed exclusively in male germ cells and a validated biomarker of male infertility. TEX101 was suggested to function as a cell surface chaperone of numerous proteins involved in sperm migration and sperm-egg interaction. However, the precis...
ORGANISM(S): Homo sapiens (Human) 
2018-11-21 | PXD008333 | Pride
A disintegrin and metalloproteinase domain-containing protein 29  interactome  testis-specific proteins  spermatozoa  single nucleotide polymorphism (snp)  deleterious variant  unexplained infertility Tex101  testis-expressed sequence 101 protein  ly6k  lymphocyte antigen 6 complex Locus k  adam29 
UnknownImmunocapture-Selected Reaction Monitoring Screening Facilitates the Development of ELISA for the Measurement of Native TEX101 in Biological Fluids.
Not available
S-EPMC4458717 | biostudies-literature
UnknownStructural, Functional and Phylogenetic Analysis of Sperm Lysozyme-Like Proteins.
Not available
S-EPMC5104373 | biostudies-literature
UnknownCharacterization of the shrimp neuroparsin (MeNPLP): RNAi silencing resulted in inhibition of vitellogenesis.
Not available
S-EPMC4244560 | biostudies-literature
TranscriptomicsThe effect of Crem absence on gene expression in mouse testis.
CREM (cAMP responsive element modulator) together with CREB and ATF-1 belong to the CREB family of transcriptional factors, that respond to cyclic AMP signaling and bind to cAMP responsive element (CRE) sites in promoters of selected genes. CREM can produce isoforms that have either activating or re...
ORGANISM(S): Mus musculus 
2012-04-10 | E-GEOD-29593 | biostudies-arrayexpress
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