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ClinicalMulticenter Phase II Study of Transanal TME (taTME)
Radical rectal cancer resection, namely total mesorectal excision (TME), is the cornerstone of the treatment of resectable rectal cancer. In combination with chemotherapy and radiation treatment (CRT), complete TME with negative resection margins is associated with sustained local and systemic contr...
2243734 | ecrin-mdr-crc
GenomicsIL-2wt and IL-2nα differentially reshape the TME
IL-2wt and IL-2nα differentially reshape the TME
PRJEB57697 | ENA
TranscriptomicsGene chip (Clariom S) analysis of 12 corresponding pairs of TECs and NECs from human colorectal carcinoma patients from different prognostic TMEs (Th1-TME vs Control-TME)
Tumor endothelial cells (TECs) and corresponding normal endothelial cells (NECs) were isolated from 12 different human colocrectal carcinoma (CRC) patients with different prognostic tumor microenvironments (TME: Th1-TME vs Control-TME).
ORGANISM(S): Homo sapiens 
2023-05-01 | E-MTAB-10465 | biostudies-arrayexpress
GenomicsInfiltrating B cells and tertiary lymphoid structures in the TME
Infiltrating B cells and tertiary lymphoid structures in the TME
PRJNA780577 | ENA
GenomicsSingle cell RNA sequencing of the in vivo mouse TME
Single cell RNA sequencing of the in vivo mouse TME
PRJNA1118670 | ENA
TranscriptomicsIL-2wt and IL-2nα differentially reshape the TME
Comparing two agonists of interleukin-2 (IL-2), IL-2wt and IL-2nα, differentially reshape the tumor microenvironment (TME). To more comprehensively explore the mechanisms by which the two different IL-2R agonists regulate the TME, we performed single-cell RNA sequencing (scRNA-seq) on immune cells i...
ORGANISM(S): Mus musculus 
2023-04-02 | E-MTAB-12373 | biostudies-arrayexpress
TranscriptomicsTesticular germ cell tumour cells release microRNA containing extracellular vesicles that induce phenotypic and genotypic changes in cells of the tumour microenvironment
Malignant germ-cell-tumours (GCTs) are characterised by microRNA (miRNA/miR-) dysregulation, with universal over-expression of miR-371~373 and miR-302/367 clusters regardless of patient age, tumour site, or subtype (seminoma/yolk-sac-tumour/embryonal carcinoma). These miRNAs are released into the bl...
ORGANISM(S): Homo sapiens 
2023-09-30 | E-MTAB-13322 | biostudies-arrayexpress
GenomicsThe glucose-deprived tumor microenvironment (TME) drives the senescence of adoptively transferred Th9 cells.
The glucose-deprived tumor microenvironment (TME) drives the senescence of adoptively transferred Th9 cells.
PRJNA1335106 | ENA
UnknownThe prospect of tumor microenvironment-modulating therapeutical strategies.
Not available
S-EPMC9772844 | biostudies-literature
GenomicsTranscriptomic Analysis Reveals TME-Mediated Macrophage IFIT1 Upregulation and CX3CR1 Suppression Drive Osteosarcoma Progression
Transcriptomic Analysis Reveals TME-Mediated Macrophage IFIT1 Upregulation and CX3CR1 Suppression Drive Osteosarcoma Progression
PRJNA1306604 | ENA
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