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ProteomicsProteome analysis of formalin-fixed paraffin-embedded colorectal adenomas reveals the heterogeneous nature of Traditional Serrated Adenoma compared to the other colorectal adenomas
Traditional serrated adenoma (TSA) remains the least understood of all the colorectal adenomas although these lesions have been associated with a significant cancer risk- twice that of the conventional adenoma (CAD) and of the sessile serrated adenoma (SSA/P). This study was performed to investigat...
ORGANISM(S): Homo sapiens (Human) 
2020-01-21 | PXD014511 | Pride
Colon adenoma  label free quantification  proteomics  formalin-fixed paraffin-embedded  ffpe  sessile serrated adenoma  traditional serrated adenoma  orbitrap fusion 
GenomicsDiscovery of traditional serrated adenoma by using DSP
Discovery of traditional serrated adenoma by using DSP
PRJEB60272 | ENA
TranscriptomicsDiscovery of traditional serrated adenoma by using DSP
To further characterized the serrated pathway, we used the novel Digital Spatial Profiling (DSP) technology and its mRNA Cancer Transcriptome Atlas (CTA) panel, which includes over 1800 target gene, to investigate the underlying gene expression changes and pathways involved in sessile serrated lesio...
ORGANISM(S): Homo sapiens 
2023-12-31 | E-MTAB-12465 | biostudies-arrayexpress
Methylation profilingAnalysis of DNA methylation in traditional serrated adenomas
We aimed to identify epigenetic alterations associated with the development of traditional serrated adenomas (TSAs). Through DNA methylation analysis with HumanMethylation450 BeadChip in TSAs and sessile serrated adenoma/polyp (SSA/Ps), we identified DNA methylation specifically associated with TSA ...
ORGANISM(S): Homo sapiens 
2018-01-01 | GSE96540 | GEO
UnknownEpigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer.
Not available
S-EPMC5797007 | biostudies-literature
UnknownDownregulation of SMOC1 is associated with progression of colorectal traditional serrated adenomas.
Not available
S-EPMC10905814 | biostudies-literature
UnknownSmall bowel intussusception caused by a serrated adenoma: a case report.
Not available
S-EPMC9793040 | biostudies-literature
Genomicsc276951a-4f9b-41a8-adc9-4f136cc59348 - samples
Dataset consists of Oncomine Comprehensive Cancer Panel v3 sequencing of 16 tumor-normal mucosa pairs. Tumors include 8 sessile serrated lesions (SSL), 3 sessile serrated lesions with dysplasia (SSL/D), 2 traditional serrated adenomas (TSA) and 3 tubular adenoma s(TA).
EGAD00001008191 | EGA
GenomicsHomo sapiens
Analysis of DNA methylation in traditional serrated adenomas
PRJNA378978 | ENA
TranscriptomicsTranscriptomic profiles of advanced colorectal adenomas from 40 Korean patients
We report the RNA-seq data of 40 advanced colorectal adenoma patients form Dongguk University Ilsan International Hospital. The polyps with a diameter of 1cm or greater were regarded as advenced colorectal adenoma and obtained through colonoscopy. The data consist of 22 tublar adenoma, 6 tublovillou...
ORGANISM(S): Homo sapiens 
2023-08-07 | GSE154548 | GEO
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