transforming growth factor-beta

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Instrument Platform

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Maxwell 16 LEV-plant RNA kit (3)
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Publication Date

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UNIPROT ID/AC

Q13485 (5)
P36897 (5)
Q15796 (4)
P01137 (4)
P37173 (2)
P48436 (1)
Q15797 (1)
Q14457 (1)
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P01583 (1)
P45452 (1)
P06238 (1)
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P17246 (1)
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Q01177 (1)
Q15116 (1)
P16410 (1)
P02458 (1)
O15105 (1)
Q99ML9 (1)
Q60698 (1)
Q05CN3 (1)
Q60979 (1)
A2A5Z6 (1)
O35253 (1)
P97471 (1)

ENSEMBL ID

ENSG00000147251 (1)
ENSG00000170477 (1)
ENSG00000247315 (1)

CHEBI ID

CHEBI:15741 (9)
CHEBI:17596 (9)
CHEBI:18257 (8)
CHEBI:16750 (8)
CHEBI:17154 (8)
CHEBI:16737 (8)
CHEBI:16919 (8)
CHEBI:15354 (8)
CHEBI:16708 (7)
CHEBI:18211 (7)
CHEBI:15891 (7)
CHEBI:17568 (7)
CHEBI:32816 (7)
CHEBI:16235 (7)
CHEBI:15428 (7)
CHEBI:16449 (7)
CHEBI:30915 (7)
CHEBI:16027 (7)
CHEBI:16335 (7)
CHEBI:17368 (7)
CHEBI:16811 (6)
CHEBI:27266 (6)
CHEBI:16704 (6)
CHEBI:17750 (6)
CHEBI:15682 (6)
CHEBI:16040 (6)
CHEBI:17361 (6)
CHEBI:26523 (2)
CHEBI:35222 (1)
CHEBI:18367 (1)

Metabolite Name

Choline (10)
Creatine (9)
Inosine (9)
Taurine (8)
Guanosine (8)
Creatinine (8)
Hypoxanthine (8)
AMP (7)
Uracil (7)
Betaine (7)
Ornithine (7)
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Niacinamide (6)
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L-Carnitine (6)
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CMP (5)
Piperidine (5)
Indole (5)
Methionine (5)
L-Proline (5)
Threonine (5)
L-Tryptophan (5)
Uric acid (5)

First Public Date

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Modelling Approach

Ordinary differential equation model (9)
Fuzzy logic model (1)
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Study status

Terminated (1)
Recruiting (1)
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Lab affiliation

Department of Molecular Biology and Genetics (2)
Department of Molecular Biology and Genetics, Aarhus University, Denmark (2)
Head Proteomics Group, Leiden University Medical Center, Center for Proteomics and Metabolomics, PO Box 9600, Postal zone P1-Q, 2300 RC Leiden, The Netherlands (2)
Institute of Lung Biology and Disease and Comprehensive Pneumology Center, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, German (2)
SIMM (2)
Aarhus University, Department of Molecular Biology and Genetics (1)
Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, 90089, USA Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine of USC, Los Angeles, CA, 90033, USA (1)
Arkana Laboratories, 10810 Executive Center Drive, Little Rock, Arkansas 72211 (1)
BK21 Plus KNU Multi-Omics-based Creative Drug Research Team, College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Republic of Korea (1)
Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Old Road, University of Oxford, Oxford OX3 7LD, UK (1)
Center for Translational Research and Molecular Biology of Cancer, Maria Sklodowska-Curie National Research Institute of Oncology Gliwice Branch, Gliwice, Poland (1)
Conway Institute Research Fellow Special Lecturer in Clinical Pharmacology School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland. (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington 98109, USA (1)
Department of Biology, Technion-Israel Institute of Technology, Haifa, Israel (1)
Department of Cardiology, Medical University Hospital, Heidelberg, Germany (1)
Department of Chemistry & Chemical Biology, Northeastern University (1)
Department of Hematopoiesis, Sanquin Research, Amsterdam, The Netherlands (1)
Department of Laboratory Medicine and Pathology Mayo Clinic 200 First Street SW Rochester, MN 55905, USA (1)
Department of Ophthalmology, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai 200072, China. (1)
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Department of Physical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland (1)
Dept Physiology/CellBiophysics, Columbia University Medical Center, New York, NY 10032 (1)
Dept of Molecular Biology and Genetics, Aarhus University,8000- Aarhus, Denmark (1)
Dept. Applied Tumor Biology Institute of Pathology Im Neuenheimer Feld 224 69120 Heidelberg Germany (1)
Division of Cancer Research, Ninewells Hospital and Medical School, University of Dundee, James Arrott Drive, DD1 9SY, Dundee, UK (1)
Functional Proteomics Laboratory, Department of Science and Technology, Federal University of Sao Paulo, UNIFESP, Sao Jose dos Campos, Sao Paulo, Brazil (1)
Institute for Anatomy and Cell Biology Dept. Molecular Embryology Albert-Ludwigs-University Freiburg Germany (1)
Institute of Exptl. Internal Medicine University Magdeburg Medical Faculty Leipziger Str. 44 Magdeburg, Germany (1)
Institute of Molecular Biology and Tumor Research (IMT) Center for Tumor Biology and Immunology (ZTI) Philipps-Universität Marburg (1)

Keyword

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Location

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Expression data from A549 cells after treatment with flagellin and transforming growth factor beta 1

We have examined the changes in gene expression aftert reatment of A549 cells, a cultured alveolar epithelial cells, with flagellin and transforming growth factor beta 1. In this dataset, we include the expression data obtained from A549 cells after treatment with purified flagellin or transforming...

ORGANISM(S): Homo sapiens

2012-10-31 | E-GEOD-38309 | biostudies-arrayexpress

Protease profiling of liver fibrosis reveals the ADAM metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of transforming growth factor beta

During chronic liver disease, tissue remodeling leads to dramatic changes and accumulation of matrix components. Matrix metalloproteases and their inhibitors have been involved in the regulation of matrix degradation. However, the role of other proteases remains incompletely defined. We undertook a ...

ORGANISM(S): Homo sapiens

2012-01-05 | E-GEOD-24667 | biostudies-arrayexpress

Transcription profiling of human MCF10A cells subjected to ionizing radiation and treatment with transforming growth factor beta-1.

Transforming growth factor beta-1 (TGFbeta) is a tumor suppressor during the initial stage of tumorigenesis, but it can switch to a tumor promoter during neoplastic progression. Ionizing radiation (IR), both a carcinogen and a therapeutic agent, induces TGFbeta activation in vivo. We now show that I...

ORGANISM(S): Homo sapiens

2008-11-08 | E-GEOD-8240 | biostudies-arrayexpress

Protein accumulation post-LASIK surgery in granular corneal dystrophy type II patients involves altered proteolytic processing of transforming growth factor beta-induced protein (TGFBIp)

his study present the protein profile of diseased cornea from granular corneal dystrophy patients developing protein accumulation after LASIK surgery. Extracted ion chromatography (XIC) label free quantification was perform using Mascot Distiller software. In addition, 2D-PAGE followed by western bl...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-10-04 | MSV000080219 | MassIVE

Protection of the prodomain α1-helix correlates with latency in the transforming growth factor-β family

The 33 members of the transforming growth factor beta (TGF-β) family are fundamentally important for organismal development and homeostasis. Family members are synthesized and secreted as pro-complexes of non-covalently associated prodomains and growth factors (GF). Pro-complexes from a subset of fa...

ORGANISM(S): Homo sapiens (Human)

2022-01-19 | PXD026841 | Pride

Enhanced Pathogenicity of Th17 cells Generated in the Absence of Transforming Growth Factor-β Signaling

CD4+ T cells that selectively produce interleukin (IL)-17, are critical for host defense and autoimmunity1-4. Crucial for T helper17 (Th17) cells in vivo5,6, IL-23 has been thought to be incapable of driving initial differentiation. Rather, IL-6 and transforming growth factor (TGF)-β1 have been argu...

ORGANISM(S): Mus musculus

2010-08-31 | E-GEOD-23505 | biostudies-arrayexpress

Transforming growth factor beta 1 induces methylation changes in lung fibroblasts

PRJNA557426 | ENA

The transcriptional regulators TAZ and YAP direct Transforming Growth Factor-beta-induced tumorigenic phenotypes in breast cancer cells

Uncontrolled Transforming growth factor-beta (TGFβ) signaling promotes aggressive metastatic properties in late-stage breast cancers. However, how TGFβ-mediated cues are directed to induce late-stage tumorigenic events is poorly understood, particularly given that TGFβ has clear tumor suppressing ac...

ORGANISM(S): Homo sapiens

2014-04-02 | E-GEOD-56445 | biostudies-arrayexpress

Transforming growth factor beta 1 induces methylation changes in lung fibroblasts [Affymetrix]

PRJNA557430 | ENA

Transforming growth factor beta 1 induces methylation changes in lung fibroblasts [Illumina]

PRJNA557428 | ENA

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