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Center for Physiology and Pathophysiology, Institute of Vegetative Physiology, University of Köln, Köln, Germany Cologne Excellence Cluster on Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany (lab head)
(1)
Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany; Cardio-Pulmonary Institute, Frankfurt am Main, Germany
(1)
Institute of Biochemistry and Molecular Biology I, University Clinics and Faculty of Medicine, Heinrich-Heine University Düsseldorf, Germany
(1)
Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki; Helsinki, Finland.
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Tags
xref:PubMed:36383135
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xref:PubMed:28867657
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Cardiac mtDNA and oxidative stress
Overexpression of twinkle protects cardiomyocytes from genotoxic stress caused by SOD2 heterozygocity
ORGANISM(S):
Mus musculus
2013-11-01
|
E-MEXP-3983
|
biostudies-arrayexpress
Cite
Human mitochondrial DNA helicase TWINKLE is both an unwinding and annealing helicase.
Not available
S-EPMC3340288
|
biostudies-literature
Cite
Structural insight and characterization of human Twinkle helicase in mitochondrial disease.
Not available
S-EPMC9371709
|
biostudies-literature
Cite
Method for the structural analysis of Twinkle mitochondrial DNA helicase by cryo-EM.
Not available
S-EPMC9398961
|
biostudies-literature
Cite
Structural and dynamic basis of DNA capture and translocation by mitochondrial Twinkle helicase.
Not available
S-EPMC9723800
|
biostudies-literature
Cite
Structural basis for adPEO-causing mutations in the mitochondrial TWINKLE helicase.
Not available
S-EPMC6423418
|
biostudies-literature
Cite
The hexameric structure of the human mitochondrial replicative helicase Twinkle.
Not available
S-EPMC4417153
|
biostudies-literature
Cite
Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase.
Not available
S-EPMC7186178
|
biostudies-literature
Cite
Mutations in Twinkle primase-helicase cause Perrault syndrome with neurologic features.
Not available
S-EPMC4248451
|
biostudies-literature
Cite
Human mitochondrial helicase Twinkle has RNA binding, annealing, and strand-exchange activities.
Not available
S-EPMC12820530
|
biostudies-literature
Cite
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