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TranscriptomicsThe ubiquitin-conjugating enzyme HR6B is required for maintenance of X chromosome silencing in mouse spermatocytes and spermatids
Background: The ubiquitin-conjugating enzyme HR6B is required for spermatogenesis in mouse. Loss of HR6B results in aberrant histone modification patterns on the trancriptionally silenced X and Y chromosomes (XY body) and on centromeric chromatin in meiotic prophase. We studied the relationship betw...
ORGANISM(S): Mus musculus 
2010-05-27 | E-GEOD-21749 | biostudies-arrayexpress
GenomicsUBE2J1 is the E2 Ubiquitin Conjugating Enzyme Required for Androgen Receptor Degradation
UBE2J1 is the E2 Ubiquitin Conjugating Enzyme Required for Androgen Receptor Degradation
PRJNA1003118 | ENA
GenomicsAn E2 ubiquitin conjugating enzyme links diubiquitinated H2B to H3K27M oncohistone function
An E2 ubiquitin conjugating enzyme links diubiquitinated H2B to H3K27M oncohistone function
PRJNA1149477 | ENA
ProteomicsIs transthyretin a regulator of Ubc9 SUMOylation?
Ageing and mutations of transthyretin (TTR), the thyroid hormones and retinol transporting protein lead to amyloidosis by destabilizing the structure of TTR. Because protein structure is regulated through posttranslational modifications, we investigated the Small Ubiquitin-like Modifier (SUMO)ylatio...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080754 | MassIVE
ProteomicsFunctional conservation and divergence of the helix-turn-helix motif of E2 ubiquitin-conjugating enzymes
Supporting .raw data for "Functional conservation and divergence of the helix-turn-helix motif of E2 ubiquitin-conjugating enzymes", DOI: 10.15252/embj.2021108823 Related to Figure 1E and EV1A.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-17 | MSV000088403 | MassIVE
GenomicsModulation of proteostasis by the ubiquitin-conjugating enzyme UBE2N in immunoproteasome-positive AML
Modulation of proteostasis by the ubiquitin-conjugating enzyme UBE2N in immunoproteasome-positive AML
PRJNA1207531 | ENA
UnknownA giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors.
Not available
S-EPMC2132795 | biostudies-literature
ProteomicsIdentification by activity-based probes of a new Plasmodium falciparum E2 ubiquitin conjugating enzyme
The ubiquitin-proteasome system (UPS) is essential for Plasmodium falciparum survival and represents a potential target for antimalarial therapies. We utilized a ubiquitin-based activity probe (Ub-Dha) to capture active ubiquitin conjugating machinery during asexual blood-stage development. Several ...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2025-03-13 | PXD056473 | Pride
Plasmodium falciparum Activity proteomics Ubiquitin 
GenomicsPredictive potential of circulating Ube2h mRNA as an E2 ubiquitin-conjugating enzyme for diagnosis or treatment of Alzheimer’s disease
Predictive potential of circulating Ube2h mRNA as an E2 ubiquitin-conjugating enzyme for diagnosis or treatment of Alzheimer’s disease
PRJNA616376 | ENA
TranscriptomicsE2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
Ubiquitin and ubiquitin-like proteins (UBLs) are directed to targets by cascades of E1, E2, and E3 enzymes. The largest ubiquitin E3 subclass consists of cullin-RING ligases (CRLs), which contain one each of several cullins (CUL1, -2, -3, -4, or -5) and RING proteins (RBX1 or -2). CRLs are activated...
ORGANISM(S): Mus musculus 
2009-03-23 | E-GEOD-14088 | biostudies-arrayexpress
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