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Mouse ESCs depleted of the epigenetic modifying enzyme Usp22 fail to differentiate properly. Ectopic expresison of Usp22 results in spontaneous differnetiation. In order to understand the transcriptional program underlying this biological defect, whole genome expression analysis was performed. E14 ...
ORGANISM(S): Mus musculus 
This analysis identifies genes which are affected in HCT116 cells upon USP22 knockdown
ORGANISM(S): Homo sapiens 
Transcriptional profiling of Usp22-WT and Usp22-KO pancreatic tumor cells
This analysis identifies genes which are affected in SW480 cells upon siRNA-mediated USP22 knockdown
ORGANISM(S): Homo sapiens 
This analysis identifies genes which are affected in SW837 cells upon siRNA-mediated USP22 knockdown
ORGANISM(S): Homo sapiens 
This analysis identifies genes which are affected in MCF10A cells upon siRNA-mediated USP22 knockdown
ORGANISM(S): Homo sapiens 
Dynamic control of ubiquitination by deubiquitinating enzymes is essential for almost all biological processes. Ubiquitin-specific peptidase 22 (USP22) is part of the SAGA complex and catalyzes the removal of monoubiquitination from histone H2B, thereby regulating gene transcription. However, novel ...
ORGANISM(S): Homo sapiens (Human) 
2021-05-03 | PXD020909 | Pride
ACC-MESO1 cells: Control shRNA vs USP22 shRNA
Investigating the role of USP22 in reprogramming
The analysis identifies genes which are dependent on USP22 expression in murine HER2-driven murine mammary carcinomas.
ORGANISM(S): Mus musculus 
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