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ProteomicsHuman POP analysis - Proteomics of Uterosacral Ligament Connective Tissue from Women With and Without Pelvic Organ Prolapse
Purpose: Damage to the uterosacral ligaments is an important contributor to uterine and vaginal prolapse. The aim of this study was to identify differentially expressed proteins in the uterosacral ligaments of women with and without pelvic organ prolapse and analyze their relationships to cellular...
ORGANISM(S): Homo sapiens (Human) 
2018-12-10 | PXD011467 | Pride
Ingenuity pathway analysis  itraq analysis  pelvic organ prolapse  uterosacral ligament Reproductive system 
GenomicsSingle-cell analysis of uterosacral ligament revealed cellular heterogeneity in women with pelvic organ prolapse
Single-cell analysis of uterosacral ligament revealed cellular heterogeneity in women with pelvic organ prolapse
PRJNA1054006 | ENA
TranscriptomicsGene expression profile in pelvic organ prolapse
Introduction and Hypothesis: Identify processes contributing to pelvic organ prolapse (POP) by transcriptional profiling of pelvic connective tissue in conjunction with light microscopy. Methods: We performed a frequency matched case-control study of women undergoing hysterectomy. Total RNA, extract...
ORGANISM(S): Homo sapiens 
2008-09-19 | E-GEOD-12852 | biostudies-arrayexpress
TranscriptomicsSingle-cell analysis of uterosacral ligament revealed cellular heterogeneity in women with pelvic organ prolapse
Pelvic organ prolapse (POP) markedly affects the quality of life of women, including significant financial burden. Using single-cell RNA sequencing, we constructed a transcriptional profile of 30,452 single cells of the uterosacral ligament in POP and control samples for the first time, and identifi...
ORGANISM(S): Homo sapiens 
2024-02-14 | GSE250414 | GEO
UnknownTotal Vaginal Hysterectomy With Uterosacral Ligament Suspension Compared With Supracervical Hysterectomy With Sacrocervicopexy for Uterovaginal Prolapse.
Not available
S-EPMC8376791 | biostudies-literature
UnknownAssociation Between Enlarged Genital Hiatus and Composite Surgical Failure After Vaginal Hysterectomy With Uterosacral Ligament Suspension.
Not available
S-EPMC10132998 | biostudies-literature
UnknownInflammatory Cells in Control and Prolapsed Uterosacral Ligament Tissue.
Not available
S-EPMC11438740 | biostudies-literature
UnknownSupramolecular Fibrous Hydrogel Augmentation of Uterosacral Ligament Suspension for Treatment of Pelvic Organ Prolapse.
Not available
S-EPMC11468651 | biostudies-literature
UnknownUltrasound of the Uterosacral Ligament, Parametrium, and Paracervix: Disagreement in Terminology between Imaging Anatomy and Modern Gynecologic Surgery.
Not available
S-EPMC7865545 | biostudies-literature
TranscriptomicsDifferential gene expression in uterosacral ligament from patients with recurrent and primary pelvic organ prolapse
Objective: The objective of this study was to profile differential gene expression in three distinct patient groups. Study Design: The groups consisted of women with recurrent POP, women with primary POP and women without POP. Whole human genome DNA microarrays were used to evaluate differential gen...
ORGANISM(S): Homo sapiens 
2019-03-27 | GSE28660 | GEO
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