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Peroxisome proliferator-activated receptor alpha (PPARα) is a key regulator of hepatic fat oxidation that serves as an energy source during starvation. Vanin-1 has been described as a putative PPARα target gene in liver, but its function in hepatic lipid metabolism is unknown. We investigated the ...
ORGANISM(S): Mus musculus 
Vanin-1 deficiency enhances host tolerance to influenza infection by modulating cellular redox status
Peroxisome proliferator-activated receptor alpha (PPARα) is a key regulator of hepatic fat oxidation that serves as an energy source during starvation. Vanin-1 has been described as a putative PPARα target gene in liver, but its function in hepatic lipid metabolism is unknown. We investigated the re...
ORGANISM(S): Mus musculus 
2014-04-24 | GSE51712 | GEO
Host survival during infection depends on the balance between pathogen resistance and tissue tolerance mechanisms. Although resistance pathways are well-characterized, the molecular determinants of host tolerance remain poorly understood. Here we demonstrate that vanin-1, an ectoenzyme known for its...
ORGANISM(S): Mus musculus 
2026-06-22 | GSE298514 | GEO
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