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1-Methylhistidine Attenuates Early Myocardial Inflammation in Type 3 Cardiorenal Syndrome through Modulation of the p105/p50 NF-κB Axis
This study investigated the myocardial transcriptional response to 1-methylhistidine (1-MH) in type 3 cardiorenal syndrome (CRS3). CRS3 was induced in male Wistar rats by bilateral renal ischemia-reperfusion. Left ventricular tissues were collected 24 h after reperfusion from CRS rats and CRS rats t...
ORGANISM(S): Rattus norvegicus 
2026-09-30 | GSE344175 | GEO
Click chemistry based substrates screening for METTL9 in Mettl9 KO MEF cells.
ORGANISM(S): Mus Musculus (mouse) 
Post-translational methylation plays a crucial role in regulating and optimizing protein function. Protein histidine methylation, occurring as the two isomers 1- and 3- methylhistidine (1MH and 3MH), was first reported five decades ago, but remains largely unexplored. Here we report that METTL9 is a...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2020-11-23 | PXD022067 | Pride

Urinary metabolites and their concentrations serve as biomarkers for identification of metabolic pathways that relate to specific diseases; therefore, fast and accurate quantification of the metabolites in urine is essential in health assessment and diagnosis. As many urinary metabolites are of p...

2026-06-08 | MTBLS13986 | MetaboLights

We examined the effects of ketone monoester (KME) and carbohydrate (CHO) co-ingestion on exogenous CHO oxidation, metabolomic responses and exercise capacity. In a randomised repeated-measures design (after a 36 h CHO loading protocol and pre-exercise meal of 12 and 2 g.kg-1, respectively), eight...

2026-04-22 | MTBLS6260 | MetaboLights
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