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MetabolomicsSingle-cell and bulk level metabolomic study of the glycolysis inhibition by 2-deoxy-D-glucose in Saccharomyces cerevisiae
Single-cell level measurements are necessary to characterize the intrinsic biological variability in a population of cells. In a study of the metabolic response of a clonal Saccharomyces cerevisiae population challenged by the glycolytic inhibitor 2-deoxy-D-glucose (2-DG), this variability is shown ...
2013-05-22 | MTBLS29 | MetaboLights
ProteomicsProteomic analysis of mouse hearts treated with and without 2-deoxy-D-glucose
2-deoxy-D-glucose (2DG) is a glucose analog that is established to inhibit glucose metabolism via glycolysis. It has long been recognized as a potential chemical mimetic of calorie restriction, and it also has been shown to have anti-viral effects in infected cells, against among others SARS-CoV-2. ...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-20 | PXD027974 | Pride
Heart Differential proteomics 2-deoxy-d-glucose (2dg) Nutrient metabolism 
TranscriptomicsDeep sequencing of endogenous mRNA from Caenorhabditis elegans in the presence of 2-deoxy-D-glucose (DOG) at 4 different time points
Background: C. elegans fed with a chemical inhibitor of glucose, namely 2-deoxy-D-glucose (DOG), exhibit considerably extended life span. DOG, in contradiction to D-glucose, cannot be metabolized in the glycolytic pathway. This results in the fact that less glucose is available for ATP production, a...
ORGANISM(S): Caenorhabditis elegans 
2013-11-06 | E-GEOD-46344 | biostudies-arrayexpress
TranscriptomicsModulation of immunomodulatory peptide activity by 2-deoxy-d-glucose
The goal of this study was to identify the role of glycolysis in the activity of immunomodulatory peptides with respect to macrophage function using the glycolytic inhibitor 2-deoxy-d-glucose
ORGANISM(S): Homo sapiens 
2016-10-29 | GSE74508 | GEO
TranscriptomicsDeep sequencing of endogenous mRNA from Caenorhabditis elegans in the presence of 2-deoxy-D-glucose (DOG) at 4 different time points
Background: C. elegans fed with a chemical inhibitor of glucose, namely 2-deoxy-D-glucose (DOG), exhibit considerably extended life span. DOG, in contradiction to D-glucose, cannot be metabolized in the glycolytic pathway. This results in the fact that less glucose is available for ATP production, a...
ORGANISM(S): Caenorhabditis elegans 
2013-11-06 | GSE46344 | GEO
GenomicsHomo sapiens
Modulation of immunomodulatory peptide activity by 2-deoxy-d-glucose
PRJNA300622 | ENA
Genomics
Macrophages treated with 2-deoxy-D-glucose
PRJNA668376 | ENA
UnknownProtocol to measure glucose utilization in mouse tissues using radiolabeled 2-deoxy-D-glucose.
Not available
S-EPMC11656071 | biostudies-literature
Unknown2-Deoxy-2-fluoro-d-glucose metabolism in Arabidopsis thaliana.
Not available
S-EPMC4630959 | biostudies-literature
ProteomicsQuantitative phosphoproteomic analysis of Chromochloris zofingiensis under glucose, 2‑deoxy‑D‑glucose and AZD‑8055 treatments
This study aims to explore the protein phosphorylation regulatory mechanism of the microalgae Chromochloris zofingiensis in response to carbon source variation and mTOR pathway inhibition. A total of four experimental groups were set up, including control group, glucose treatment group, 2-deoxy-D-gl...
ORGANISM(S): Chromochloris Zofingiensis 
2026-09-01 | PXD083531 |
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