Sort   by:  
 Page size 
MetabolomicsSingle-cell and bulk level metabolomic study of the glycolysis inhibition by 2-deoxy-D-glucose in Saccharomyces cerevisiae
Single-cell level measurements are necessary to characterize the intrinsic biological variability in a population of cells. In a study of the metabolic response of a clonal Saccharomyces cerevisiae population challenged by the glycolytic inhibitor 2-deoxy-D-glucose (2-DG), this variability is shown ...
2013-05-22 | MTBLS29 | MetaboLights
ProteomicsProteomic analysis of mouse hearts treated with and without 2-deoxy-D-glucose
2-deoxy-D-glucose (2DG) is a glucose analog that is established to inhibit glucose metabolism via glycolysis. It has long been recognized as a potential chemical mimetic of calorie restriction, and it also has been shown to have anti-viral effects in infected cells, against among others SARS-CoV-2. ...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-20 | PXD027974 | Pride
Heart Differential proteomics 2-deoxy-d-glucose (2dg) Nutrient metabolism 
TranscriptomicsDeep sequencing of endogenous mRNA from Caenorhabditis elegans in the presence of 2-deoxy-D-glucose (DOG) at 4 different time points
Background: C. elegans fed with a chemical inhibitor of glucose, namely 2-deoxy-D-glucose (DOG), exhibit considerably extended life span. DOG, in contradiction to D-glucose, cannot be metabolized in the glycolytic pathway. This results in the fact that less glucose is available for ATP production, a...
ORGANISM(S): Caenorhabditis elegans 
2013-11-06 | E-GEOD-46344 | biostudies-arrayexpress
TranscriptomicsModulation of immunomodulatory peptide activity by 2-deoxy-d-glucose
The goal of this study was to identify the role of glycolysis in the activity of immunomodulatory peptides with respect to macrophage function using the glycolytic inhibitor 2-deoxy-d-glucose
ORGANISM(S): Homo sapiens 
2016-10-29 | GSE74508 | GEO
Genomics
Macrophages treated with 2-deoxy-D-glucose
PRJNA668376 | ENA
GenomicsHomo sapiens
Modulation of immunomodulatory peptide activity by 2-deoxy-d-glucose
PRJNA300622 | ENA
Unknown2-Deoxy-2-fluoro-d-glucose metabolism in Arabidopsis thaliana.
Not available
S-EPMC4630959 | biostudies-literature
TranscriptomicsDeep sequencing of endogenous mRNA from Caenorhabditis elegans in the presence of 2-deoxy-D-glucose (DOG) at 4 different time points
Background: C. elegans fed with a chemical inhibitor of glucose, namely 2-deoxy-D-glucose (DOG), exhibit considerably extended life span. DOG, in contradiction to D-glucose, cannot be metabolized in the glycolytic pathway. This results in the fact that less glucose is available for ATP production, a...
ORGANISM(S): Caenorhabditis elegans 
2013-11-06 | GSE46344 | GEO
UnknownProtocol to measure glucose utilization in mouse tissues using radiolabeled 2-deoxy-D-glucose.
Not available
S-EPMC11656071 | biostudies-literature
TranscriptomicsTranscription profiling of human cancer cells treated with unfolded protein response modulators under endoplasmic reticulum stress conditions
The unfolded protein response (UPR) is a cellular defense mechanism against glucose deprivation, a cell condition that occurs in solid tumors. A key feature of the UPR is the activation of the transcription program that allows the cell to cope with endoplasmic reticulum (ER) stress. We used micoarra...
ORGANISM(S): Homo sapiens 
2009-06-01 | E-GEOD-13548 | biostudies-arrayexpress
Sort   by:  
 Page size