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BACKGROUND: Novel biomarkers are urgently needed to distinguish between benign and malignant thyroid nodules and detect thyroid cancer in the early stage. The associations between serum IgG N-glycosylation and thyroid cancer risk have been revealed. We aimed to explore the potent...

2021-09-01 | MTBLS2935 | MetaboLights
IgA nephropathy (IgAN) is the most common primary glomerular disease. The characteristic pathology involves immune complexes formed by the deposition of IgA1 and underglycosylated IgA1 aggregates in the mesangial area, which may be accompanied by the deposition of IgG and/or IgM and complement compo...
ORGANISM(S): Homo sapiens 
2020-10-07 | GSE159123 | GEO
The glycosylation of B cell-derived IgG is altered in the setting of obesity, and it contributes to obesity-related insulin resistance. With obesity in both humans and mice a key glycan on the Fc region of IgG is deficient in galactose and in the terminal sialic acid that is linked to galactose. How...
ORGANISM(S): Homo sapiens 
2026-09-23 | GSE270270 | GEO
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