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MetabolomicsAlleviation of Loperamide-Induced Constipation by Lactiplantibacillus plantarum SYS1: Role of Properistaltic Metabolites and Promotion of Enteric Nerve Development via 5-HT4R Activation

Background: Constipation is a common gastrointestinal disorder. Lactobacillus plantarum has been reported to have the effect of relieving constipation, but its underlying mechanism remains unclear.

Results: Lactiplantibacillus plantarum SYS1 was identified through in ...

2025-08-06 | MTBLS12821 | MetaboLights
GenomicsPaenibacillus sp. KN14-4R isolate:KN14-4R
Paenibacillus sp. KN14-4R isolate:KN14-4R Genome sequencing
PRJNA1282422 | ENA
GenomicsPaenibacillus sp. PK1-4R
Paenibacillus rostockiensis PK1-4R Genome sequencing
PRJNA974575 | ENA
GenomicsMicrobacterium sp. 4R-513
Microbacterium sp. 4R-513 Genome sequencing
PRJNA607820 | ENA
GenomicsFull genome sequence of Microbacterium sp. 4R-513
Full genome sequence of Microbacterium sp. 4R-513 Genome sequencing
PRJNA532277 | ENA
GenomicsRummeliibacillus sp. JY-2-4R
Rummeliibacillus sp. JY-2-4R Genome sequencing
PRJNA1371722 | ENA
GenomicsHuman iPSC 4R tauopathy model uncovers modifiers of tau propagation [scRNA-seq]
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation [scRNA-seq]
PRJNA1076934 | ENA
Genomics4R-Tau Seeding Activity Reveals Molecular Subtypes in Progressive Supranuclear Palsy
4R-Tau Seeding Activity Reveals Molecular Subtypes in Progressive Supranuclear Palsy
PRJNA1289105 | ENA
GenomicsHuman iPSC 4R tauopathy model uncovers modifiers of tau propagation [bulk RNA-seq]
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation [bulk RNA-seq]
PRJNA1076936 | ENA
TranscriptomicsHuman iPSC 4R tauopathy model uncovers modifiers of tau propagation [scRNA-seq]
Tauopathies are age-associated neurodegenerative diseases whose mechanistic underpinnings remain elusive, partially due to lack of appropriate human models. Here, we engineered new human induced pluripotent stem cell (hiPSC)-derived neuronal lines to express 4R Tau and 4R Tau carrying the P301S MAPT...
ORGANISM(S): Homo sapiens 
2024-04-08 | GSE255904 | GEO
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