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UnknownSynergising single-cell resolution and 4sU labelling boosts inference of transcriptional bursting.
Not available
S-EPMC10276402 | biostudies-literature
Transcriptomics4sU metabolic labeled transcripts in 65 YRI LCLs
Noncoding variants play a central role in the genetics of complex traits, but we still lack a full description of the main molecular pathways through which they act. Here we used molecular data to quantify the contribution of cis-acting genetic effects at each major stage of gene regulation from chr...
ORGANISM(S): Homo sapiens 
2016-03-29 | E-GEOD-75220 | biostudies-arrayexpress
UnknownCorrecting 4sU induced quantification bias in nucleotide conversion RNA-seq data.
Not available
S-EPMC11039982 | biostudies-literature
GenomicsLabelling transcriptional response to dissociation using SLAMseq
Labelling transcriptional response to dissociation using SLAMseq
PRJNA837586 | ENA
TranscriptomicsMeasurement of temperature affects on Arabidopsis transcription and decay rates
The goal of this study is to measure Arabidopsis mRNA transcription and mRNA decay rates genome wide at two temperatures, and thus to calculate the temperature coefficient of both processes. Sensing and response to ambient temperature is important for controlling growth and development of many organ...
ORGANISM(S): Arabidopsis thaliana 
2013-12-07 | E-GEOD-53071 | biostudies-arrayexpress
GenomicsLabelling transcriptional response to dissociation in mouse hippocampus using scSLAMseq
Labelling transcriptional response to dissociation in mouse hippocampus using scSLAMseq
PRJNA837256 | ENA
TranscriptomicsSLAM-Seq analysis of Ythdf2-deficient pre-leukemic cells
The mRNA m6A reader YTHDF2 is overexpressed in a broad spectrum of human acute myeloid leukemias (AML). To study the role of YTHDF2 on mRNA decay rates in leukemia, c-Kit+ cells from foetal livers of Ythdf2fl/fl; Vav-iCre (Ythdf2CKO) and Ythdf2fl/fl (Ythdf2CTL) 14.5 dpc embryos were transduced with...
ORGANISM(S): Mus musculus 
2019-04-05 | E-MTAB-7784 | biostudies-arrayexpress
GenomicsLabelling transcriptional response to dissociation in zebrafish larvae using scSLAMseq
Labelling transcriptional response to dissociation in zebrafish larvae using scSLAMseq
PRJNA902669 | ENA
TranscriptomicsRNA-sequencing using SLAM-sequencing protocol of human iPSC-derived lower motor neurons treated with BDNF for 1, 2, 6 h
SLAM-sequencing was performed on i3 LMNs following protocols adapted from Herzog et al. (2017). Three biological replicates of i3 LMNs were treated with 100 µM 4sU (Control) + labelling medium or 100 µM 4sU + BDNF (BDNF condition) labelling medium on Day 7 for 1h, 2h, and 6h. Cells were washed with ...
ORGANISM(S): Homo sapiens 
2025-05-30 | E-MTAB-14537 | biostudies-arrayexpress
GenomicsMapping Human Transient Transcriptomes Using Single Nucleotide Resolution 4sU Sequencing (SNU-Seq)
Mapping Human Transient Transcriptomes Using Single Nucleotide Resolution 4sU Sequencing (SNU-Seq)
PRJNA746479 | ENA
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