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TranscriptomicsTranscription profiling of human THP-1 cells in response to treatment with lipo-polysaccharide for 1 or 4 hours
Effect of LPS in a time dependent manner (1hr or 4hr treatment v untreated) on the THP-1 cell using a focused microarray containing 465 putative or known NF-kappaB regulated genes.
ORGANISM(S): Homo sapiens 
2006-09-29 | E-MEXP-868 | biostudies-arrayexpress
GenomicsFunctional link between Rad2 and Mediator
In this study, we generate genomic maps of Mediator, Rad2, Pol II, TBP and TFIIH, by ChIP coupled to next generation sequencing technology (ChIP-seq), in wild type strains from Saccharomyces cerevisiae. A related study involving ChIP-chip analysis of Rad2 occupany is also deposited at ArrayExpress ...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-01 | E-MTAB-1595 | biostudies-arrayexpress
UnknownAn autoinhibitory role for the GRF zinc finger domain of DNA glycosylase NEIL3.
Not available
S-EPMC7667957 | biostudies-literature
TranscriptomicsJHI Pa MC mutants
Plant cell wall degrading enzymes (PCWDEs) are key virulence determinants in the pathogenesis of the potato pathogen, Pectobacterium atrosepticum. In this study, we report the impact on virulence of a transposon insertion mutation in the metJ gene that codes for the repressor of the methionine biosy...
ORGANISM(S): Pectobacterium atrosepticum 
2012-11-02 | E-MTAB-1167 | biostudies-arrayexpress
TranscriptomicsRad2 ChIP-chip experiment
This aim of this experiment is to assess the genome-wide Rad2 occupancy in yeast Saccharomyces cerevisiae by ChIP-chip, in the absence of exogenous genotoxic stress. A related study involving ChIP-seq analysis of Rad2 occupany is also deposited at ArrayExpress under accession number E-MTAB-1595 ( ww...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-01 | E-MEXP-3875 | biostudies-arrayexpress
UnknownGain of 1q As a Prognostic Biomarker in Wilms Tumors (WTs) Treated With Preoperative Chemotherapy in the International Society of Paediatric Oncology (SIOP) WT 2001 Trial: A SIOP Renal Tumours Biology Consortium Study.
Not available
S-EPMC5505170 | biostudies-literature
TranscriptomicsDoxorubicin resistance in a novel in vitro model of human pleomorphic liposarcoma associated with ALT
Soft tissue sarcomas are a diverse set of fatal human tumors where few agents have demonstrable clinical efficacy, with the standard therapeutic combination of doxorubicin and ifosfamide showing only a 25-30% response rate in large multi-institutional trials. Although liposarcomas are the most commo...
ORGANISM(S): Homo sapiens 
2010-03-03 | E-GEOD-19449 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Candida albicans in response to a sudden availability of glucose in the extracellular medium, having previously been grown on a non-fermentable carbon source
We investigated how Candida albicans adapts its transcriptional pattern to a sudden availability of glucose in the extracellular medium, having previously grown on a non-fermentable carbon source.
ORGANISM(S): Candida albicans 
2008-06-01 | E-MEXP-1151 | biostudies-arrayexpress
UnknownThe UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain.
Not available
S-EPMC3314968 | biostudies-literature
TranscriptomicsMethylome analysis of normal kidney, nephrogenic rest and Wilms tumor
Genome wide DNA methylation profiling of normal kidney (n=36), nephrogenic rest (n=22) and Wilms tumour (n=37) was performed using the Illumina 450k array. Two papers were composed after analysis of this data (1) describes comparative analysis of 22 matched normal kidney-Wilms tumour pairs which ide...
ORGANISM(S): Homo sapiens 
2014-07-08 | E-GEOD-59157 | biostudies-arrayexpress
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