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TranscriptomicsTranscription profiling of mouse mutant abcb4 (-/-)
Molecular factors governing liver pathology in abcb4 (-/-) mice. Dr. Nakken, Karl Esten, Dr. Berge, Knut E., Dr. Knut J. Labori, Ståle Nygård, Dr. Terese Haaland , professor Morten G. Ræder. Institute for Experimental Medical Research and Department of Pathology, Ulleval University Hospital, Oslo...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-4603 | biostudies-arrayexpress
TranscriptomicsExpression levels of xenobiotic transporters in kideny of Abcb4-null mice
The renal clearance of perfluorooctanoic acid (PFOA) increased in Abcb4 null mice compared with wild type mice, especially in male Abcb4 null mice. We evaluated the expression changes of transporters in kidney of male Abcb4 null mice by using microarray to reveal the candidate transporters of PFOA. ...
ORGANISM(S): Mus musculus 
2011-06-21 | E-GEOD-30084 | biostudies-arrayexpress
TranscriptomicsMolecular characterization of two unrelated patients ABCB4 deletions
To allow acute characterization of ABCB4 locus constitutional deletion in two patients with cholelithiasis/cholestasis, an Agilent 2X400 array CGH was used. Goal was to obtain genomic rearrangements fine characterization in order to describe ABCB4 constitutional deletions. ABCB4 locus microdeletions...
ORGANISM(S): Homo sapiens 
2011-10-04 | E-GEOD-28676 | biostudies-arrayexpress
TranscriptomicsAbcb4 liver expression profiling
The multidrug resistance gene 2 (Mdr2 or Abcb4) encodes a P-glycoprotein (Pgp) - a phospholipid flippase - that is the murine orthologue of the MDR3 gene in humans. The MDR2 protein is principally expressed in the bile canalicular membrane of the liver. A homozygous disruption of Abcb4 causes absenc...
ORGANISM(S): Mus musculus 
2011-08-01 | GSE26699 | GEO
TranscriptomicsAbcb4 liver expression profiling
The multidrug resistance gene 2 (Mdr2 or Abcb4) encodes a P-glycoprotein (Pgp) - a phospholipid flippase - that is the murine orthologue of the MDR3 gene in humans. The MDR2 protein is principally expressed in the bile canalicular membrane of the liver. A homozygous disruption of Abcb4 causes absenc...
ORGANISM(S): Mus musculus 
2011-07-31 | E-GEOD-26699 | biostudies-arrayexpress
TranscriptomicsMolecular and metabolic effects of norUDCA in Abcb4 knockout mice
To identify (i) target genes relevant for the disease development (WT vs. Abcb4-/- mice) and (ii) to gain insights into mechanisms leading to the reversal of chronic cholestatic liver injury in Abcb4-/- mice treated with the side-chain modified bile acid "norUDCA" (Abcb4-/- mice vs. norUDCA treated ...
ORGANISM(S): Mus musculus 
2011-02-02 | GSE26547 | GEO
GenomicsMolecular characterization of two unrelated patients ABCB4 deletions
To allow acute characterization of ABCB4 locus constitutional deletion in two patients with cholelithiasis/cholestasis, an Agilent 2X400 array CGH was used. Goal was to obtain genomic rearrangements fine characterization in order to describe ABCB4 constitutional deletions.
ORGANISM(S): Homo sapiens 
2011-10-05 | GSE28676 | GEO
TranscriptomicsExpression levels of xenobiotic transporters in kideny of Abcb4-null mice
The renal clearance of perfluorooctanoic acid (PFOA) increased in Abcb4 null mice compared with wild type mice, especially in male Abcb4 null mice. We evaluated the expression changes of transporters in kidney of male Abcb4 null mice by using microarray to reveal the candidate transporters of PFOA.
ORGANISM(S): Mus musculus 
2011-06-21 | GSE30084 | GEO
TranscriptomicsMolecular factors governing liver pathology in abcb4 (-/-) mice
Molecular factors governing liver pathology in abcb4 (-/-) mice. Dr. Nakken, Karl Esten, Dr. Berge, Knut E., Dr. Knut J. Labori, Ståle Nygård, Dr. Terese Haaland , professor Morten G. Ræder. Institute for Experimental Medical Research and Department of Pathology, Ulleval University Hospital, Oslo, N...
ORGANISM(S): Mus musculus 
2007-04-01 | GSE4603 | GEO
UnknownA PDZ-Like Motif in the Biliary Transporter ABCB4 Interacts with the Scaffold Protein EBP50 and Regulates ABCB4 Cell Surface Expression.
Not available
S-EPMC4720445 | biostudies-literature
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