Sort   by:  
 Page size 
UnknownPotential protective association of the AA genotype and a allele of CXCR4 rs2228014 polymorphism with COVID-19 severity in adult egyptians.

Background

By the end of December 2019, a new coronavirus, termed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged, and the cause of the disease was named coronavirus disease 2019 (COVID-19). Several genetic factors have been implicated in diverse responses to SARS-CoV-2...
S-EPMC11479566 | biostudies-literature
UnknownGlycylglycine promotes the solubility and antigenic utility of recombinant HCV structural proteins in a point-of-care immunoassay for detection of active viremia.

Background

Although E. coli is generally a well-opted platform for the overproduction of recombinant antigens as heterologous proteins, the optimization of expression conditions to maximize the yield of functional proteins remains empirical. Herein, we developed an optimized E. coli (BL21)-b...
S-EPMC10795219 | biostudies-literature
UnknownStrategic foliar nutrition with Sorbitol, Mannitol, and Boron improves physiological performance and yield in Faba beans on reclaimed sandy soil.
Under natural field stress conditions in newly reclaimed sandy soils characterized by extreme diurnal temperature fluctuations (ΔT > 20 °C, peak temperatures 42 °C), limited water retention, and moderate salinity, faba bean cultivation faces significant yield stability challenges. This study evaluat...
S-EPMC12834954 | biostudies-literature
UnknownValidation of the Diagnostic and Prognostic Values of ADAMTS5 and FSTL1 in Osteoarthritis Rat Model.

Objective

Osteoarthritis (OA) is a global public health problem and a leading cause of morbidity and disability. Due to lack of sensitive and specific tools for early OA diagnosis and predicting prognosis, the availability of new reliable and sensitive biomarkers is a widely appreciated need...
S-EPMC8804805 | biostudies-literature
UnknownHeart failure in Europe: Guideline-directed medical therapy use and decision making in chronic and acute, pre-existing and de novo, heart failure with reduced, mildly reduced, and preserved ejection fraction - the ESC EORP Heart Failure III Registry.

Aims

We analysed baseline characteristics and guideline-directed medical therapy (GDMT) use and decisions in the European Society of Cardiology (ESC) Heart Failure (HF) III Registry.

Methods and results

Between 1 November 2018 and 31 December 2020, 10 162 patients with acute HF (AHF, ...
S-EPMC11683873 | biostudies-literature
UnknownLaparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study.

Background

Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in the availability of laparoscopic appendectomy, alternative management choices, and outcomes are poorly described. The aim was to identify variation in surgi...
S-EPMC6061087 | biostudies-literature
UnknownGlobal economic burden of unmet surgical need for appendicitis.

Background

There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis.

Methods

Data on the incidence of appendicitis from 1...
S-EPMC10364778 | biostudies-literature
UnknownDeterminants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries.

Background

Child health is a key priority on the global health agenda, yet the provision of essential and emergency surgery in children is patchy in resource-poor regions. This study was aimed to determine the mortality risk for emergency abdominal paediatric surgery in low-income countries ...
S-EPMC5321375 | biostudies-literature
UnknownGlobal variation in anastomosis and end colostomy formation following left-sided colorectal resection.

Background

End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection.

Metho...

S-EPMC6921967 | biostudies-literature
UnknownElective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries.

Background

The 2015 Lancet Commission on global surgery identified surgery and anaesthesia as indispensable parts of holistic health-care systems. However, COVID-19 exposed the fragility of planned surgical services around the world, which have also been neglected in pandemic recovery planni...
S-EPMC9621702 | biostudies-literature
Sort   by:  
 Page size