Among the childhood diseases, B-cell acute lymphocytic leukemia (B-ALL) is the most frequent type of cancer. In spite of recent advances concerning disease treatment, cytotoxic chemotherapy remains as the first line of treatment in several countries, and the modifications induced by such drugs in th...
Model for the activation of SLUG, SIP1, TWIST1, and NF-κB (subunits p50 and p65). The model exhibits two stationary states (bistability), each corresponding to the gene expression profiles we determined from HER2+ and TNBC breast cancer cell lines.
