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MetabolomicsMulti-omics reveals the protective mechanisms of Gastrodia elata ethyl acetate extract in vascular dementia

Objective: This study aimed to investigate the ameliorative effect of the ethyl acetate extract of Gastrodia elata (EEGE) on vascular dementia (VD) and its underlying mechanisms. 

Methods: A VD rat model was established using the two-vessel occlusion method, while an in vitro cerebral ...

2026-01-15 | MTBLS13695 | MetaboLights
MetabolomicsAlistipes putredinis Alleviates Metabolic-Associated Fatty Liver Disease via the Acetate-GPR43 Axis by Suppressing Neutrophil ROS Generation

Background & Aims:

Intestinal dysbiosis contributes to the pathogenesis of metabolic-associated fatty liver disease (MAFLD), though precise bacterial targets and mechanisms remain incompletely elucidated. This study investigated whether the depletion of Alistipes putredinis (AP) in adol...

2026-01-15 | MTBLS13691 | MetaboLights
MetabolomicsAlistipes putredinis Alleviates Metabolic-Associated Fatty Liver Disease via the Acetate-GPR43 Axis by Suppressing Neutrophil ROS Generation

Background & Aims:

Intestinal dysbiosis contributes to the pathogenesis of metabolic-associated fatty liver disease (MAFLD), though precise bacterial targets and mechanisms remain incompletely elucidated. This study investigated whether the depletion of Alistipes putredinis (AP) in adol...

2026-01-15 | MTBLS13694 | MetaboLights
MetabolomicsAlistipes putredinis Alleviates Metabolic-Associated Fatty Liver Disease via the Acetate-GPR43 Axis by Suppressing Neutrophil ROS Generation

Background & Aims:

Intestinal dysbiosis contributes to the pathogenesis of metabolic-associated fatty liver disease (MAFLD), though precise bacterial targets and mechanisms remain incompletely elucidated. This study investigated whether the depletion of Alistipes putredinis (AP) in adol...

2026-01-16 | MTBLS13699 | MetaboLights
TranscriptomicsResponse of Escherichia coli to acetate concentration during growth on glucose
E. coli MG1655 was grown on M9 minimal medium supplemented with 15mM glucose and either 0, 10, 50 or 100 mM acetate. Transcriptomic analysis from exponential growing cells was performed using Agilent microarray A-MEXP-2232. This work was done with the help of students during practicals. Consequentl...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2020-08-21 | E-MTAB-9086 | biostudies-arrayexpress
TranscriptomicsResponse of Escherichia coli to acetate in presence of 100 mM methyl α-D-glucopyranoside
This experiment was performed to challenge E. coli response to acetate when its growth rate flux is reduced by 40% with 100 mM methyl α-D-glucopyranoside. Control without inhibition in the exact same conditions was already published on ArrayExpress database (accession number E-MTAB-9086) and could ...
ORGANISM(S): Escherichia coli K-12 
2022-09-23 | E-MTAB-11717 | biostudies-arrayexpress
TranscriptomicsEffect of acetate during Escherichia coli switch from N-Acetyl Glucosamine to Malate
This experiment was performed to challenge E. coli response to acetate when switched from N-Acetyl Glucosamine (NAG) to malate as the main substrate. Here, E. coli BW25113 strain was grown in M9 medium complemented with 15 mM NAG, The cells were grown to mid-exponential phase in shake flasks at 37...
ORGANISM(S): Escherichia coli K-12 
2026-05-12 | E-MTAB-16650 | biostudies-arrayexpress
TranscriptomicsRNA-seq of mouse iBAT with local acetate administration
Acetate, or CFMB (Gpr43 agonist), or saline were administrate to left lobe of interscapular brown adipose tissue (iBAT) by a catheter guided pump. Tissue were harvested after four and seven days of administration.
ORGANISM(S): Mus musculus 
2021-11-20 | E-MTAB-10680 | biostudies-arrayexpress
TranscriptomicsAnalysis of aortic gene expression in ovariectomized ApoE-deficient mice substituted with medroxyprogesterone acetate, norethisterone acetate or placebo
Agilent 4x44k Whole Mouse Genome v1 Microarrays were used to analyze aortic transcriptome of mice substituted with medroxyprogesterone acetate, norethisterone acetate or placebo after having been ovariectomized. The aim of this experiment was to detect genes regulated in the gestagen-treated groups ...
ORGANISM(S): Mus musculus 
2014-06-30 | E-GEOD-57972 | biostudies-arrayexpress
ProteomicsEvaluation of NHS-Acetate and DEPC labelling for determination of solvent accessible amino acid residues in protein complexes
The structural analysis of proteins and protein complexes is key for understanding their function and regulation. In order to gain structural information, we examined protein surface labelling using NHS-Acetate and DEPC following an MS-based workflow. Using two model proteins we characterise the obt...
ORGANISM(S): Oryctolagus cuniculus cuniculus Saccharomyces cerevisiae (Baker's yeast) 
2020-05-05 | PXD015940 | Pride
Diethylpyrocarbonate N-hydroxysuccinimidyl acetate Mass spectrometry Neutral loss Chemical labelling Solvent accessible surface area Labelling percentage 
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