Sort   by:  
 Page size 
MetabolomicsEx-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study
Osteoarthritis (OA) is an age-related degenerative musculoskeletal disease characterised by loss of articular cartilage, synovitis, abnormal bone proliferation and subchondral bone sclerosis. Underlying OA pathogenesis is yet to be fully elucidated with no OA specific biomarkers in clinical use. Ex-...
2020-09-30 | MTBLS1495 | MetaboLights
UnknownData detailing the platelet acetyl-lysine proteome.
Not available
S-EPMC4726637 | biostudies-literature
ProteomicsDisruption of acetyl-lysine turnover in muscle mitochondria promotes insulin resistance and redox stress without overt respiratory dysfunction
A double knockout (DKO) mouse model harboring muscle-specific deficits in acetyl CoA buffering by carnitine acetyltransferase (CrAT), and lysine deacetylation by SIRT3, resulted in additive hyperacetylation of the mitochondrial proteome, which was augmented exponentially by chronic high fat feeding....
ORGANISM(S): Mus musculus (Mouse) 
2019-11-25 | PXD014586 | Pride
Protein acetylation Mitochondrial bioenergetics Insulin resistance 
UnknownThe cardiac acetyl-lysine proteome.
Not available
S-EPMC3699649 | biostudies-literature
ProteomicsAdaptation of white adipocytes to cooler temperatures: adipocytes cultured at either 37°C or 31°C
This study investigates how differentiated white adipocytes adapt to cooler temperatures by remodeling their acetyl-lysine–modified proteome. Differentiated adipocytes were cultured at 37°C or 31°C for 12 days to induce temperature-dependent physiological and biochemical changes. To profile acetylat...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-07 | PXD079423 | Pride
Adipocytes cultured at either 37°c or 31°c Acetyl‑lysine proteomics 
ProteomicsChemical proteomics profiling of N-terminal and lysine acetyltransferases
Acetylation of amino groups is a prevalent protein modification in all kingdoms of life. Acetyl groups are transferred from Coenzyme A (CoA) to protein N-termini and lysine side chains by N-terminal acetyltransferases (NATs) and lysine acetyltransferases (KATs), respectively. Building on lysine-CoA ...
ORGANISM(S): Homo Sapiens (human) 
2021-04-14 | PXD018544 | JPOST Repository
MetabolomicsThe “ForensOMICS” approach to forensic post-mortem interval estimation: combining metabolomics, lipidomics and proteomics for the analysis human skeletal remains
Not available
ORGANISM(S): Homo sapiens 
ST002283 | MetabolomicsWorkbench
UnknownThe Acetyl Group Buffering Action of Carnitine Acetyltransferase Offsets Macronutrient-Induced Lysine Acetylation of Mitochondrial Proteins.
Not available
S-EPMC4754083 | biostudies-literature
ProteomicsInvestigating peptide-Coenzyme A-conjugates as chemical probes for proteomic profiling of N-terminal and lysine acetyltransferases
Acetyl groups are transferred from Acetyl-Coenzyme A (Ac-CoA) to protein N-termini and lysine side chains by N-terminal acetyltransferases (NATs) and lysine acetyltransferases (KATs), respectively. Building on lysine-CoA conjugates as KAT probes, we have synthesized peptide probes with CoA conjugate...
ORGANISM(S): Homo Sapiens (human) 
2022-05-02 | PXD032957 | JPOST Repository
ProteomicsKansl2 dependent acetylome study in primary Kansl2 (fl/fl) murine embryonic fibroblasts
As one of the most important post-translational protein modifications, lysine acetylation is catalyzed by lysine acetyltransferases (KATs), which catalyze the covalent attachment of an acetyl group to the N epsilon–residue of lysine. The histone acetyltransferase MOF, which represents the main histo...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-05 | PXD038521 | Pride
Kat8 regulatory nsl complex subunit 2  mef (murine embryonic fibroblast)  primary inducible kansl2 knock-out  cre-ert2  anti acetyl-lysine antibody  ptm enrichment 
Sort   by:  
 Page size