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MetabolomicsMetabolic Rewiring of Bacterial Subpopulations Governs Polymyxin Responses in Acinetobacter baumannii
Polymyxins are often last-resort antibiotics against high-priority Gram-negative pathogens, particularly Acinetobacter baumannii. However, most mechanistic studies to date have overlooked the heterogeneity within bacterial populations during polymyxin treatment. Using time-lapse imaging and propidiu...
2026-07-27 | MTBLS14745 | MetaboLights
MetabolomicsInvestigating the Impact of Acinetobacter lwoffii-ECT1/E6E7 Co-culture Metabolites on Cervical Cell Proliferation and Apoptosis via Untargeted Metabolomics.

This study employed untargeted metabolomics detection combined with bioinformatics analysis to investigate the metabolites from the co-culture of Acinetobacter lwoffiiand cervical precancerous cells ECT1/E6E7. A. lwoffiiwas co-cultured with ECT1/E6E7 cells at an MOI of 100. The culture supernatan...

2025-12-17 | MTBLS13526 | MetaboLights
MetabolomicsL-serine enables reducing the virulence of Acinetobacter baumannii and modulating the SIRT1 pathway to eliminate the pathogen

The emergence of high-virulent Acinetobacter baumannii strains increases the mortality of patients and seriously affects their prognosis, which motivates us to explore novel ways to control such infections. In this study, gas chromatography-mass spectrometry was adopted to explore the me...

2024-01-18 | MTBLS8966 | MetaboLights
TranscriptomicsTranscription profiling of Acinetobacter baumannii multi-drug resistant strain and a susceptible reference strain - Abefflux
Transcriptomic comparison of a multidrug resistant Acinetobacter baumannii strain and a susceptible reference strain.
ORGANISM(S): Acinetobacter baumannii 
2009-11-20 | E-MEXP-2254 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of ATCC 17978hm Acineotbacter baumannii strain and CpdA mutant
Difference in RNA expression levels between Acinetobacter baumannii cells expressing high and low levels of cyclic AMP Total RNA obtained from Acineotbacter baumannii bacterial cells in Log phase gown in MH broth culture, isolated RNA in triplicate from three expreiment. cpdA::Tn mutant and 17978hm ...
ORGANISM(S): Acinetobacter baumannii 
2015-06-21 | E-GEOD-64935 | biostudies-arrayexpress
TranscriptomicsComparative transcriptional analysis of Acinetobacter baumannii strain ATCC 17978 and strain 17978hm
In this study the transcriptomes of Acinetobacter baumannii strains ATCC 17978 and 17978hm were compared. Strain 17978hm is a hns knockout derivative of strain ATCC 17978. Strain 17978hm displays a hyper-motile phenotype on semi-solid Mueller-Hinton (MH) media (0.25% agar). ATCC 17978 and 17978hm fr...
ORGANISM(S): Acinetobacter baumannii 
2013-08-05 | E-GEOD-40681 | biostudies-arrayexpress
ProteomicsSoDA-PAL Protein Profiling Proteomics of Sorgoleone Catabolizing Microbial Isolate Acinetobacter pittii SO1
Photoaffinity probe-based protein labeling of microbial isolate Acinetobacter pittii SO1 (NCBITAXON:48296), isolated from the sorghum rhizosphere that can utilize sorgoleone as a sole carbon source in order to identify proteins that bind sorgoleone. Photoaffinity labeling of A. pittii lysates using ...
ORGANISM(S): Acinetobacter Pittii (ncbitaxon:48296) 
2023-05-18 | MSV000091986 | MassIVE
MetabolomicsMetabolomic and Cultivation Insights into the Tolerance of the Spacecraft-Associated Acinetobacter Towards Kleenol 30, a Cleanroom Floor Detergent
Not available
ORGANISM(S): Acinetobacter 
ST002380 | MetabolomicsWorkbench
TranscriptomicsRNA-Seq of Acinetobacter baumannii ATCC 17978 and a gene knockout strain of putative response regulator gene A1S_2006 from the ATCC 17978 background
The putative response regulator gene A1S_2006 of Acinetobacter baumannii ATCC 17978 was knocked out using a homologous recombination method to assess the effects of that gene knockout in a global transcriptome landscape. This was done with an objective to better understand the cellular processes tha...
ORGANISM(S): Acinetobacter baumannii 
2019-04-04 | E-MTAB-7815 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses of Acinetobacter baumannii ATCC 17978 to limiting iron availability
A. baumannii ATCC 17978 cells were incubated under iron replete (mueller-hinton) and iron limiting (MH + 200 µM 2,2'-dipyridyl) conditions, total RNA was extracted when cultures reached OD600=0.7. The probes on the microarray cover all predicted open reading frames (at least 4 per ORF) and addition...
ORGANISM(S): Acinetobacter baumannii 
2013-10-18 | E-GEOD-24921 | biostudies-arrayexpress
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