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MetabolomicsMetabolic Rewiring of Bacterial Subpopulations Governs Polymyxin Responses in Acinetobacter baumannii
Polymyxins are often last-resort antibiotics against high-priority Gram-negative pathogens, particularly Acinetobacter baumannii. However, most mechanistic studies to date have overlooked the heterogeneity within bacterial populations during polymyxin treatment. Using time-lapse imaging and propidiu...
2026-07-27 | MTBLS14745 | MetaboLights
MetabolomicsL-serine enables reducing the virulence of Acinetobacter baumannii and modulating the SIRT1 pathway to eliminate the pathogen

The emergence of high-virulent Acinetobacter baumannii strains increases the mortality of patients and seriously affects their prognosis, which motivates us to explore novel ways to control such infections. In this study, gas chromatography-mass spectrometry was adopted to explore the me...

2024-01-18 | MTBLS8966 | MetaboLights
TranscriptomicsRNA sequencing of ATCC 17978hm Acineotbacter baumannii strain and CpdA mutant
Difference in RNA expression levels between Acinetobacter baumannii cells expressing high and low levels of cyclic AMP Total RNA obtained from Acineotbacter baumannii bacterial cells in Log phase gown in MH broth culture, isolated RNA in triplicate from three expreiment. cpdA::Tn mutant and 17978hm ...
ORGANISM(S): Acinetobacter baumannii 
2015-06-21 | E-GEOD-64935 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Acinetobacter baumannii multi-drug resistant strain and a susceptible reference strain - Abefflux
Transcriptomic comparison of a multidrug resistant Acinetobacter baumannii strain and a susceptible reference strain.
ORGANISM(S): Acinetobacter baumannii 
2009-11-20 | E-MEXP-2254 | biostudies-arrayexpress
TranscriptomicsComparative transcriptional analysis of Acinetobacter baumannii strain ATCC 17978 and strain 17978hm
In this study the transcriptomes of Acinetobacter baumannii strains ATCC 17978 and 17978hm were compared. Strain 17978hm is a hns knockout derivative of strain ATCC 17978. Strain 17978hm displays a hyper-motile phenotype on semi-solid Mueller-Hinton (MH) media (0.25% agar). ATCC 17978 and 17978hm fr...
ORGANISM(S): Acinetobacter baumannii 
2013-08-05 | E-GEOD-40681 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses of Acinetobacter baumannii ATCC 17978 to limiting iron availability
A. baumannii ATCC 17978 cells were incubated under iron replete (mueller-hinton) and iron limiting (MH + 200 µM 2,2'-dipyridyl) conditions, total RNA was extracted when cultures reached OD600=0.7. The probes on the microarray cover all predicted open reading frames (at least 4 per ORF) and addition...
ORGANISM(S): Acinetobacter baumannii 
2013-10-18 | E-GEOD-24921 | biostudies-arrayexpress
TranscriptomicsSix strains of Acinetobacter Baumannii: RNAseq data analysis
We performed RNAseq for gene expression analysis for six strains of Acinetobacter Baumannii isolated from blood samples (defined as strains 1, 2, 3, 4 and 6) of patients hospitalized at the University Hospital \\"San Giovanni di Dio e Ruggi d'Aragona\\" (Salerno, Italy)
ORGANISM(S): Acinetobacter baumannii 
2023-09-01 | E-MTAB-13274 | biostudies-arrayexpress
ProteomicsAcinetobacter baumannii membrane proteome
Different digestion methods and extraction detergents were examined for membrane proteome sample preparation, and label-free quantitative proteome analysis of the polymyxin B induced Acinetobacter baumannii ATCC 19606 membrane proteome were performed based on nano LC-MS/MS.
ORGANISM(S): Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841 
2021-09-13 | PXD026714 | Pride
Acinetobacter baumannii  membrane proteome 
ProteomicsSecretome of Acinetobacter baumannii KAB strains
We analyzed the extracellular proteome of colistin-resistant Korean Acinetobacter baumannii (KAB) strains to identify proteome profiles that can be used to characterize extensively drug-resistant KAB strains.
ORGANISM(S): Acinetobacter baumannii 
2020-05-27 | PXD015959 | Pride
Mrab Acinetobacter baumannii Secretome 
GenomicsChIP-seq analysis of H-NS in Acinetobacter baumannii AB5075
The experiment contains ChIP-seq data for Acinetobacter baumannii strain AB5075 encoding 3xFLAG tagged H-NS. Experiments were done with or without ectopic expression of the truncated H-NS-39 protein (corresponding to the H-NS multimerization surface). The strain was grown at 37 degrees in LB medium ...
ORGANISM(S): Acinetobacter baumannii 
2024-07-15 | E-MTAB-13790 | biostudies-arrayexpress
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