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TranscriptomicsAzole Resistance Mechanism in Candida glabrata Oropharyngeal Isolates
Microarray was used to analyze azole resistance of Candida glabrata oropharyngeal isolates from 7 hematopoietic stem cell transplant recipients receiving fluconazole prophylaxis. Transcriptional profiling of the sequential-paired clinical isolates by microarray revealed 19 genes upregulated in the m...
ORGANISM(S): Candida glabrata 
2010-07-07 | E-GEOD-21352 | biostudies-arrayexpress
TranscriptomicsAzole Resistance Mechanism in Candida glabrata
Microarray was used to analyze azole resistance of Candida glabrata oropharyngeal isolates from 7 hematopoietic stem cell transplant recipients receiving fluconazole prophylaxis. Transcriptional profiling of the sequential-paired clinical isolates by microarray revealed 19 genes upregulated in the m...
ORGANISM(S): Candida glabrata 
2010-07-07 | E-GEOD-21355 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of an azole-resistant Candida parapsilosis isolate [posaconazole].
Azole resistance was induced in vitro by growth of a susceptible C. parapsilosis isolate in the presence of posaconazole. Whole genome microarrays were used to compare the transcriptional response of the posaconazole-resistant and susceptible isolates. Transcriptional profile of an in vitro derived ...
ORGANISM(S): Candida parapsilosis 
2011-04-18 | E-GEOD-27407 | biostudies-arrayexpress
ProteomicsA proteomic landscape of Candida albicans in the stepwise evolution to fluconazole resistance
As an opportunistic fungal pathogen, Candida albicans is a major cause of superficial and systemic infections in immunocompromised patients. The increasing rate of azole resistance in C. albicans has brought further challenges to clinical therapy. In this study, we collect five isogenic C. albicans ...
ORGANISM(S): Candida albicans (Yeast) 
2022-02-23 | PXD031774 | Pride
Candida albicans Acquired azole resistance Quantitative proteomics 
TranscriptomicsTranscription profile of an azole resistant mutant of Mycobacterium truberculosis
We used DNA microarrays to detect differentially expresses genes in a spontaneous mutant of Mycobacterium tuberculosis H37Rv resistant to azoles. We identified three adjacent upregulated genes encoding a transcription regulatory protein and two membrane proteins belonging to the family of RND efflux...
ORGANISM(S): Mycobacterium tuberculosis 
2008-07-31 | E-GEOD-12302 | biostudies-arrayexpress
TranscriptomicsContribution of CgPDR1-regulated genes in enhanced virulence of azole-resistant Candida glabrata (part 1)
In this study, we aimed to determine genome-wide changes in gene expression driven by seven individual CgPDR1 hyperactive alleles as compared to wild-type allele to identify i) the CgPdr1p target genes differentially expressed in presence of CgPDR1 hyperactive alleles and ii) potential virulence fa...
ORGANISM(S): Candida glabrata 
2010-12-31 | E-GEOD-23827 | biostudies-arrayexpress
GenomicsMycoremediation of copper-azole wood preservatives by Phanerochaete chrysosporium with a focus on resistance mechanisms and azole detoxification
Mycoremediation of copper-azole wood preservatives by Phanerochaete chrysosporium with a focus on resistance mechanisms and azole detoxification
PRJNA1197371 | ENA
TranscriptomicsTranscription profiling by array to investigate susceptibility to multiple azole resistance in Candida glabrata
Transcriptomics analysis of the evolution of a C. glabrata clinical isolate (044) from azole susceptibility to posaconazole resistance (21st day), clotrimazole resistance (31st day) and fluconazole and voriconazole resistance (45th day), induced by longstanding incubation with fluconazole (16mg/mL).
ORGANISM(S): [Candida] glabrata 
2018-11-16 | E-MTAB-6787 | biostudies-arrayexpress
TranscriptomicsAzole Resistance Mechanism in Candida glabrata
Microarray was used to analyze azole resistance of Candida glabrata oropharyngeal isolates from 7 hematopoietic stem cell transplant recipients receiving fluconazole prophylaxis. Transcriptional profiling of the sequential-paired clinical isolates by microarray revealed 19 genes upregulated in the m...
ORGANISM(S): Nakaseomyces glabratus Nakaseomyces glabratus CBS 138 
2010-07-07 | GSE21355 | GEO
UnknownThe Molecular Basis of the Intrinsic and Acquired Resistance to Azole Antifungals in Aspergillus fumigatus.
Not available
S-EPMC11678245 | biostudies-literature
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