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TranscriptomicsDevelopment of GRO-cap (GRO-seq followed by 5'-cap enrichment) to map transcription start sites in C. elegans
Dosage Compensation is required to correct for uneven gene dose between the sexes. We utilized global run-on sequencing (GRO-seq) to examine how Caenorhabditis elegans dosage compensation reduces transcription of X-linked genes. To facilitate these experiments, we required accurate 5M-bM-^@M-^Y-ends...
ORGANISM(S): Caenorhabditis elegans 
2013-06-18 | E-GEOD-43085 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of the radicle and micropylar endosperm cap of Lepidium seeds during germination in ABA
An experiment was performed to compare global transcription patterns in two tissues of Lepidium sativum seeds at different times during imbibition leading up to, but not including, radicle protrusion from the seed (e.g. germination). RNA extractions from the two tissues were hybridised to CATMA Arab...
ORGANISM(S): Lepidium sativum 
2010-10-02 | E-TABM-743 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of the radicle and micropylar endosperm cap of Lepidium seeds during germination in control medium
An experiment was performed to compare global transcription patterns in three tissues of Lepidium sativum seeds at different times during imbibition leading up to, but not including, radicle protrusion from the seed (e.g. germination). RNA extractions from the three tissues were hybridised to CATMA ...
ORGANISM(S): Lepidium sativum 
2010-06-23 | E-TABM-745 | biostudies-arrayexpress
ProteomicsA complex containing lysine-acetylated actin inhibits the formin INF2
INF2 is a member of the formin family of actin assembly factors. Dominant mis-sense mutations in INF2 link to two diseases: focal segmental glomerulosclerosis (FSGS), a kidney disease; and Charcot-Marie-Tooth disease (CMTD), a neuropathy. All disease mutations map to the autoinhibitory Diaphanous In...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2018-07-18 | MSV000082634 | MassIVE
UnknownDynamic remodeling of actin networks by cyclase-associated protein and CAP-Abp1 complexes.
Not available
S-EPMC10860761 | biostudies-literature
UnknownActin polymerization kinetics, cap structure, and fluctuations.
Not available
S-EPMC1150824 | biostudies-literature
TranscriptomicsForm and function of actin impacts actin health and aging - snRNAseq
The actin cytoskeleton is a highly conserved structural network that supports diverse cellular processes, but its contribution to organismal aging is not well understood. This project investigates how genetic and pharmacological perturbations of actin and actin-binding proteins influence global gene...
ORGANISM(S): Caenorhabditis elegans 
2026-05-07 | E-MTAB-16195 | biostudies-arrayexpress
UnknownAberrant MET activation impairs perinuclear actin cap organization with YAP1 cytosolic relocation.
Not available
S-EPMC10576810 | biostudies-literature
TranscriptomicsCap completion and CTD kinase recruitment govern the initiation-elongation transition of RNA polymerase II
After transcription initiation, RNA polymerase (Pol) II escapes from the promoter and recruits elongation factors. Here we used chromatin immunoprecipitation (ChIP) to elucidate the general initiation-elongation transition of Pol II in yeast. We extended our ChIP-chip occupancy profiling to capping ...
ORGANISM(S): Saccharomyces cerevisiae 
2013-07-30 | E-MTAB-1552 | biostudies-arrayexpress
UnknownSTEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap.
Not available
S-EPMC5974301 | biostudies-literature
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