Activity-based profiling

Show results for

Unknown (2780)
Transcriptomics (1787)
Genomics (982)
Proteomics (532)
Metabolomics (89)
Methylation profiling (56)
Other (32)
Models (4)
Clinical (2)
Genomic (1)

Organisms

Homo sapiens (1030)
Mus musculus (473)
Rattus norvegicus (69)
Arabidopsis thaliana (60)
Drosophila melanogaster (43)
Saccharomyces cerevisiae (28)
Caenorhabditis elegans (24)
Danio rerio (21)
Staphylococcus aureus (15)
Escherichia coli (13)
Bos taurus (12)
Sus scrofa (11)
synthetic construct (11)
Zea mays (10)
Gallus gallus (10)
Candida albicans (9)
Oncorhynchus mykiss (7)
Daphnia magna (5)
Xenopus laevis (5)
Schizosaccharomyces pombe (5)
Plasmodium falciparum (5)
Equus caballus (4)
Glycine max (4)
Escherichia coli str. K-12 substr. MG1655 (4)
Mycobacterium avium subsp. paratuberculosis (3)
Strongylocentrotus purpuratus (3)
Mycobacterium tuberculosis H37Rv (2)
Plasmodium falciparum K1 (1)
Plasmodium falciparum NF54 (1)
Ostreococcus tauri (1)

Organisms

Homo sapiens (411)
Mus musculus (216)
Rattus norvegicus (17)
Drosophila melanogaster (11)
Staphylococcus aureus (7)
Arabidopsis thaliana (7)
Caenorhabditis elegans (5)
Saccharomyces cerevisiae (5)
Escherichia coli (4)
Sus scrofa (3)
Danio rerio (3)
Pedobacter silvilitoris (2)
Salmonella enterica subsp. enterica serovar Typhimurium (2)
Schizosaccharomyces pombe (2)
Salmo salar (2)
Zea mays (2)
human gut metagenome (2)
Plasmodium falciparum (2)
Gallus gallus (2)
Solenopsis japonica (1)
Thermotoga maritima MSB8 (1)
Chlamydomonas moewusii (1)
Papio hamadryas (1)
Staphylococcus aureus subsp. aureus str. Newman (1)
Picea glauca (1)
Saccharopolyspora spinosa (1)
Picea engelmannii x Picea glauca (1)
Aspergillus tubingensis (1)
Apis mellifera carnica (1)
Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S (1)

Repository

biostudies-arrayexpress (1506)
ENA (870)
geo (472)
pride (390)
MetaboLights (64)
MassIVE (60)
iProX (54)
EGA (20)
MetabolomicsWorkbench (15)
jPOST (12)
GNPS (10)
PanoramaPublic (3)
BioModels (2)
PAXDB (2)
Cell Collective (1)
dbGaP (1)
FAIRDOMHub (1)
GPMDB (1)
PeptideAtlas (1)

Tissue

Cell culture (92)
Epithelial cell (37)
Colon (25)
HCT-116 cell (19)
Lung (14)
Liver (13)
Brain (12)
Permanent cell line cell (11)
Cultured cells (9)
Blood (9)
Melanocyte (8)
Leaf (8)
B cell (8)
Kidney cell (7)
Heart (7)
Kidney (7)
T cell (7)
Bacterial cells (6)
Macrophage (6)
Cell suspension culture (6)
Blood plasma (6)
Skin (5)
Blood serum (5)
Fibroblast (5)
Lung epithelium (4)
Dendritic cell (4)
HeLa cell (4)
Primary cell (4)
Hepatocyte (4)
Others (1)

Disease

Normal (10)
Leukemia (2)
Prostate carcinoma (2)
Retinoblastoma (1)
Primary acute lymphoblastic leukemia (1)
Toxicity (1)
Amyotrophic lateral sclerosis (1)
Small cell cancer (1)
HPV positive (1)
Lymphoblastic leukemia (1)
Papillary renal cell carcinoma (1)
HIV-1 and Neisseria gonorrhoeae infected (1)
High grade glioblastoma (1)
Ewing family tumor (1)
4T1 tumor-bearing (1)
Primary effusion lymphoma (PEL) (1)
Inflammatory breast carcinoma (1)
Psoriasis vulgaris (1)
Pseudomonas aeruginosa rsmA mutant infected (1)
Extranodal NK/T-Cell Lymphoma derived cell line (1)
Hepatocellular carcinoma-non tumorous region (1)
B-cell chronic lymphocytic leukemia (1)
Not applicable (1)
Cryptozoospermia (1)
Advanced atherosclerosis (1)
Pneumococcal meningitis (1)
Squamous cell carcinoma has accession C0007137 in DiseaseStateDatabase NCI_Thesaurus (1)
Glioma (1)
Apparently healthy (1)
Chronic granulomatous disease (1)

Technology Type

Mass Spectrometry (405)
Shotgun proteomics (183)
Bottom-up proteomics (118)
Affinity purification coupled with mass spectrometry proteomics (67)
Data-dependent acquisition (62)
Mass spectrometry (48)
Data-independent acquisition (31)
ESI (15)
Mass spectrometry assay (13)
Affinity proteomics (11)
SWATH MS (10)
Gel-based experiment (9)
Top-down proteomics (6)
NMR spectroscopy (3)
HDMSE (3)
SRM/MRM (3)
All-ion fragmentation (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
ILLUMINA, Illumina HiSeq 2500 (1)
ILLUMINA, Illumina HiSeq 2000 (1)
Illumina HiSeq 2000 (1)
Illumina HiSeq 2000, ILLUMINA (1)
Metaproteomics (1)
MSE (1)
DiaPASEF (1)

Instrument Platform

Illumina NovaSeq 6000 (25)
Illumina HiSeq 2500 (16)
Illumina HiSeq 4000 (13)
NextSeq 500 (11)
Illumina HiSeq 2000 (7)
NextSeq 2000 (5)
Agilent High resolution C scanner (4)
NextSeq 550 (4)
HPC cluster Lobo (2)
Controlled-environment growth chamber (short-day; 8 h light / 16 h dark) (2)
Agilent Microarray Hybridization Chamber Kit and Hybridization oven rotator (2)
Agilent G2565BA (2)
GenePix Personal 4100A [Axon Instruments] (2)
Illumina Genome Analyzer II (2)
Scanning hardware (2)
ScanArray 6000 [Perkin Elmer] (2)
None (2)
DNBSEQ-T7 (2)
Agilent TapeStation (1)
Coulter Automated Workstation Biomek i7 Hybrid (1)
RNeasy 96-well plate kit (1)
BD Rhapsody Express Instrument (1)
Novogene in-house automated library preparation system (1)
FastPrep‑24 homogenizer (MP Biomedicals) (1)
Covaris sonicator, PCR thermocycler, magnetic rack for SPRI bead clean-up (1)
Liquid-nitrogen mortar and pestle, benchtop microcentrifuge, vortex mixer (1)
Dissecting tools, liquid nitrogen, −80 °C freezer (1)
Thermocycler; magnetic rack for SPRI bead clean-up (1)
Liquid-nitrogen grinding tools; benchtop centrifuge (1)
10x genomic Chromium controller (1)

Publication Date

2013 (221)
2015 (204)
2010 (204)
2025 (194)
2014 (166)
2026 (164)
2008 (155)
2012 (148)
2011 (141)
2022 (112)
2024 (110)
2016 (99)
2023 (98)
2009 (96)
2007 (96)
2021 (66)
2017 (63)
2020 (58)
2018 (58)
2019 (50)
2006 (24)
2005 (14)
2004 (8)

UNIPROT ID/AC

LAMB3_MOUSE (2)
COLQ_MOUSE (2)
CFA53_MOUSE (2)
MMP9_MOUSE (2)
S6A14_MOUSE (2)
LOXL3_MOUSE (2)
CFA57_MOUSE (2)
SG3A2_MOUSE (2)
ABCA5_MOUSE (2)
CC151_MOUSE (2)
Q80UR4_MOUSE (2)
SPAT6_MOUSE (2)
S39A8_MOUSE (2)
MCPT8_MOUSE (2)
SP17_MOUSE (2)
VGFR1_MOUSE (2)
DLRB2_MOUSE (2)
LFNG_MOUSE (2)
PAR6B_MOUSE (2)
D3YVL2_MOUSE (2)
MIEAP_MOUSE (2)
GRAA_MOUSE (2)
CFA69_MOUSE (2)
C1QT2_MOUSE (2)
CLC1A_MOUSE (2)
M4A4D_MOUSE (2)
MUC1_MOUSE (2)
SPA6L_MOUSE (2)
CC181_MOUSE (2)
SEM3E_MOUSE (2)

ENSEMBL ID

ENSG00000247315 (1)
ENSG00000170477 (1)

CHEBI ID

CHEBI:30769 (18)
CHEBI:15428 (15)
CHEBI:28044 (15)
CHEBI:17268 (13)
CHEBI:16015 (13)
CHEBI:27897 (13)
CHEBI:17368 (13)
CHEBI:28300 (12)
CHEBI:16708 (12)
CHEBI:16610 (12)
CHEBI:15741 (12)
CHEBI:16235 (12)
CHEBI:16704 (12)
CHEBI:18012 (12)
CHEBI:30915 (12)
CHEBI:17596 (12)
CHEBI:15756 (12)
CHEBI:18344 (12)
CHEBI:24898 (11)
CHEBI:28842 (11)
CHEBI:6650 (11)
CHEBI:17568 (11)
CHEBI:17203 (11)
CHEBI:15891 (11)
CHEBI:29016 (11)
CHEBI:17295 (11)
CHEBI:26271 (10)
CHEBI:16811 (10)
CHEBI:30746 (10)
CHEBI:38068 (1)

Metabolite Name

Uracil (8)
Choline (8)
Uridine (8)
Betaine (7)
L-Proline (7)
Adenosine (7)
L-Phenylalanine (7)
Hypoxanthine (7)
Glycine (6)
Glutathione (6)
L-Arginine (6)
Indole (6)
Taurine (6)
Cholic acid (6)
Guanine (6)
Cytosine (6)
Phenylalanine (6)
L-Glutamate (6)
Glucose (6)
Adenine (6)
Creatine (6)
C17 Sphinganine (5)
C16 Sphinganine (5)
AMP (5)
Citric acid (5)
Spermidine (5)
Sucrose (5)
Niacinamide (5)
5-Methoxyindoleacetate (5)
5-Hydroxyindoleacetic acid (5)

First Public Date

2025 (160)
2026 (142)
2014 (130)
2024 (105)
2023 (59)
2019 (44)
2017 (40)
2020 (38)
2022 (34)
2018 (34)
2021 (31)
2016 (23)
2015 (21)
2013 (9)

Modelling Approach

Computational model (1)
Ordinary differential equation model (1)

Study status

Completed (2)

Lab affiliation

University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (20)
Professor of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, The Netherlands (10)
Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany (10)
Moffitt Cancer Center Tampa, FL, USA (6)
Principal Investigator Centre for Targeted Protein Degradation, School of Life Sciences (4)
Moffitt Cancer Center (3)
University Clinic for Poultry and Fish Medicine, University of Veterinary Medicine, Vienna, Austria (3)
Scripps Research (3)
Max Planck Institute for Terrestrial Microbiology Karl-von-Frisch Str. 10 35043 Marburg Germany (3)
Pacific Northwest National Laboratory, USA (3)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (3)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry ( lab head ) (2)
Division of Surgery, Oncology, and Pathology, Department of Clinical Sciences, Lund University, Solvegatan 19, 223 62, Lund, Sweden. (2)
Department of Chemistry, The Scripps Research Institute (2)
University of Missouri-Columbia (2)
GSK (2)
Department of Chemistry, Scripps Research (2)
Molecular Physiology, Leiden Institute for Chemistry, Leiden University, The Netherlands (2)
School of Biomedical Sciences and Department of Pathology, The University of Hong Kong (2)
Boston College (2)
School of Health and Life Sciences, Teesside University, UK (2)
Molecular Structure of Cell Signalling Laboratory, The Francis Crick Institute (2)
Principal Investigator • Centre for Targeted Protein Degradation (2)
University of Pennsylvania (2)
Principal Investigator Centre for Targeted Protein Degradation (2)
Aix-Marseille Univ, Inserm, CNRS, Institut Paoli-Calmettes, CRCM, Marseille Protéomique (2)
COI-NDM (University of Oxford) (2)
Chair of Proteomics and Bioanalytics, Technische Universität München, Germany (2)
IRCCS Istituto G Gaslini (2)
Molecular Oncology Chemical Biology and Molecular Medicine Moffitt Cancer Center & Research Institute, SRB3 12902 Magnolia Drive, Tampa, FL, 33612, USA. (2)

Keyword

5-Fluorouracile (1)
First line (1)
Strategy study (1)
Folinic Acid (1)
Metastatic colorectal cancer (1)
Irinotecan (1)
Cetuximab (1)

IsPrivate

False (2)

Model Flag

Non Kinetic (1)

Submitter Keywords

Ersilia (1)
FAIR-AIML (1)
Machine Learning Model (1)

Classification

bacteria (18)
fungi (4)
protozoa (3)

Modification

2x(15)N labeled L-lysine (4)
4x(15)N labeled L-arginine (4)
N6 (2)
-18.010565 (1)
-17.026549 (1)
42.010565 (1)
15.994915 (1)
57.021464 (1)
+3amu) (1)
4-tetrahydrothiazine-3-carboxylic acid (1)

Study type

Transcription profiling by array (1051)
RNA-seq of coding RNA (162)
Comparative genomic hybridization by array (51)
Unknown experiment type (45)
Other (28)
ChIP-seq (22)
RNA-seq of non coding RNA (21)
Methylation profiling by array (20)
ChIP-chip by tiling array (15)
RNA-seq of coding RNA from single cells (15)
Proteomic profiling by array (10)
Transcription profiling by tiling array (8)
Transcription profiling by RT-PCR (7)
RNA-seq of total RNA (6)
Transcription profiling by SAGE (5)
Animal - One-color microarray (4)
Animal - High-throughput sequencing (4)
Methylation profiling by high throughput sequencing (4)
RNAi profiling by array (3)
Ribo-seq (3)
MicroRNA profiling by array (3)
Human - One-color microarray (2)
ChIP-chip by array (2)
Genotyping by array (2)
Spatial transcriptomics by high-throughput sequencing (2)
Bisulfite-seq (2)
ATAC-seq (2)
Cell line - Single-cell sequencing (1)
Human - Single-cell sequencing (1)
Cell line - High-throughput sequencing (1)

Release Date

2025 (466)
2022 (306)
2021 (278)
2023 (275)
2013 (252)
2015 (251)
2014 (230)
2010 (220)
2020 (219)
2024 (213)
2016 (192)
2012 (189)
2008 (174)
2011 (173)
2019 (169)
2018 (160)
2017 (140)
2009 (119)
2026 (99)
2007 (94)
2006 (31)
2005 (20)
2004 (12)
2003 (3)
2002 (1)

Location

Italy (1)
Spain (1)
France (1)

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Characterization of Constituents with Potential Anti-Inflammatory Activity in Chinese Lonicera Species by UHPLC-HRMS Based Metabolite Profiling

This study centered on detecting potentially anti-inflammatory active constituents in ethanolic extracts of Chinese Lonicera species by taking an UHPLC-HRMS-based metabolite profiling approach. Extracts from eight different Lonicera species were subjected to both UHPLC-HRMS analysis and to pharmacol...

2022-11-17 | MTBLS3112 | MetaboLights

Activity-Based Metabolic Profiling of M. tuberculosis H37Rv Rv3208

Not available

ORGANISM(S): Mycobacterium tuberculosis H37Rv

ST000937 | MetabolomicsWorkbench

Activity-Based Metabolic Profiling of M. tuberculosis H37Rv Rv1130

Not available

ORGANISM(S): Mycobacterium tuberculosis H37Rv

ST000234 | MetabolomicsWorkbench

Activity-Based Metabolic Profiling of M. tuberculosis H37Rv Rv2247

Not available

ORGANISM(S): Mycobacterium tuberculosis H37Rv