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TranscriptomicsExpression data from actomyosin contractility regulated genes
Actomyosin contractility regulates cell morphology and movement. The objective of this study was to identify whether actomyosin contractility regulates gene expression in tumour cells and whether such genes are involved in cell morphology and movement. Gene expression analysis was carried out on h...
ORGANISM(S): Homo sapiens 
2010-08-24 | E-GEOD-23764 | biostudies-arrayexpress
TranscriptomicsMYBPH, a novel transcriptional target of NKX2-1/TTF-1, inhibits ROCK1 and actomyosin assembly, and reduces cell motility and tumor metastasis
Cell migration driven by actomyosin filament assembly is a critical step in tumour invasion and metastasis. Herein, we report identification of myosin binding protein H (MYBPH) as a transcriptional target of NKX2-1 (also known as TTF-1 and TITF1), a lineage-survival oncogene in lung adenocarcinoma. ...
ORGANISM(S): Homo sapiens 
2011-12-22 | E-GEOD-26721 | biostudies-arrayexpress
ProteomicsLinking planar polarity signaling directly to actomyosin contractility during vertebrate neurulation
Actomyosin contractility represents an ancient feature of eukaryotic cells participating in many developmental and homeostasis events, including tissue morphogenesis, muscle contraction, and cell migration, with dysregulation implicated in various pathological conditions, such as cancer. At the mol...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2024-09-19 | PXD052350 | Pride
Planar cell polarity Dishevelled Exploris 480 Vertebrates Neurulation Proteomics Prickle Actomyosin contractility 
GenomicsActomyosin-mediated tension orchestrates uncoupled respiration in adipose tissues
Actomyosin-mediated tension orchestrates uncoupled respiration in adipose tissues
PRJNA432141 | ENA
TranscriptomicsExpression data from actomyosin contractility regulated genes
Actomyosin contractility regulates cell morphology and movement. The objective of this study was to identify whether actomyosin contractility regulates gene expression in tumour cells and whether such genes are involved in cell morphology and movement. Gene expression analysis was carried out on hig...
ORGANISM(S): Homo sapiens 
2010-08-24 | GSE23764 | GEO
GenomicsCDK4 maintains cytoskeletal homeostasis by restraining actomyosin contractility
CDK4 maintains cytoskeletal homeostasis by restraining actomyosin contractility
PRJNA1481322 | ENA
GenomicsAfadin and Zyxin contribute to coupling between cell junctions and contracting actomyosin networks during apical constriction
Afadin and Zyxin contribute to coupling between cell junctions and contracting actomyosin networks during apical constriction
PRJNA843465 | ENA
TranscriptomicsKey roles for SRF in embryonic epidermal differentiation
During development, a polarized sheet of epidermal cells undergoes stratification and differentiation to produce the skin barrier. Through mechanisms poorly understood, the process involves adhesion and Notch signaling. To elucidate how epidermal embryogenesis is governed, we conditionally targeted ...
ORGANISM(S): Mus musculus 
2011-01-20 | E-GEOD-25548 | biostudies-arrayexpress
TranscriptomicsActomyosin-mediated tension orchestrates uncoupled respiration in adipose tissues
The activation of brown/beige adipose tissue (BAT) metabolism and the induction of uncoupling protein-1 (UCP1) expression are essential for BAT-based strategies to improve metabolic homeostasis. Adrenergic signaling is viewed as a key regulator of thermogenesis and UCP1-expression in BAT, while also...
ORGANISM(S): Mus musculus 
2018-03-01 | GSE109829 | GEO
GenomicsCell size regulates human endoderm specification through actomyosin-dependent AMOT-YAP signaling
Cell size regulates human endoderm specification through actomyosin-dependent AMOT-YAP signaling
PRJNA973007 | ENA
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