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Actomyosin contractility regulates cell morphology and movement. The objective of this study was to identify whether actomyosin contractility regulates gene expression in tumour cells and whether such genes are involved in cell morphology and movement. Gene expression analysis was carried out on h...
ORGANISM(S): Homo sapiens 
Actomyosin contractility represents an ancient feature of eukaryotic cells participating in many developmental and homeostasis events, including tissue morphogenesis, muscle contraction, and cell migration, with dysregulation implicated in various pathological conditions, such as cancer. At the mol...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2024-09-19 | PXD052350 | Pride
CDK4 maintains cytoskeletal homeostasis by restraining actomyosin contractility
Actomyosin contractility regulates cell morphology and movement. The objective of this study was to identify whether actomyosin contractility regulates gene expression in tumour cells and whether such genes are involved in cell morphology and movement. Gene expression analysis was carried out on hig...
ORGANISM(S): Homo sapiens 
2010-08-24 | GSE23764 | GEO
Expression data from actomyosin contractility regulated genes
Cyclin-dependent kinase 4 (CDK4) is best known for its canonical role in cell-cycle control, yet how CDK4 activity intersects with cellular architecture remains poorly defined. Here, we uncover a non-canonical function of CDK4 in maintaining cytoskeletal mechanical homeostasis in triple-negative bre...
ORGANISM(S): Homo sapiens 
2026-06-28 | GSE336354 | GEO
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