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UnknownGuidance for gynecologists utilizing telemedicine during COVID‐19 pandemic based on expert consensus and rapid literature reviews
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S-EPMC9087699 | biostudies-literature
TranscriptomicsChromatin immunoprecipitation in yeast for different affinity-tagged strains (two genotypes compared with wild type)
RNA immunoprecipitation from different affinity-tagged strains. Each hyb compared to a common total RNA.
ORGANISM(S): Schizosaccharomyces pombe 
2004-11-09 | E-MEXP-208 | biostudies-arrayexpress
TranscriptomicsExpression profiling of laser-microdissected tissue from APPPS1 plaque-depositing mouse model of Alzheimer's disease
Amyloid-M-CM-^_ (AM-CM-^_) plaques are pathological hallmarks of Alzheimer disease. However, the precise neuropathological changes that occur in brain in response to amyloid deposition are largely unknown. To study the molecular mechanism(s) responsible for AM-CM-^_-mediated neuropathology, we perfo...
ORGANISM(S): Mus musculus 
2014-11-04 | E-GEOD-15058 | biostudies-arrayexpress
TranscriptomicsClassification of a frameshift/extended and a stop mutation in WT1 as gain of function mutations which activate cell cycle genes and promote Wilms tumor cell proliferation
The Wilms tumor 1 (WT1) gene encodes a zinc finger transcription factor important for normal kidney development. WT1 is a suppressor for Wilms tumor development and an oncogene for diverse malignant tumors. We recently established cell lines from primary Wilms tumors and identified the corresponding...
ORGANISM(S): Homo sapiens 
2014-05-12 | E-GEOD-54635 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse CD4+ GFP+ (tregs) and CD4+ GFP- (Teffs) cells treated with IL-2
To obtain the molecular signature of the effect that the IL-2 therapeutic dose induces on T cells in vivo, we performed gene array analysis. Since it was critical to perform this analysis on highly purified Tregs and Teffs, and also because activated Teffs can acquire CD25 expression, we used GFP-Fo...
ORGANISM(S): Mus musculus 
2011-03-21 | E-MEXP-2689 | biostudies-arrayexpress
TranscriptomicsHeterogeneous CD3 expression levels in differing T-cell subsets account for in vivo anti-CD3-mediated immune resetting
The tolerogenic anti-CD3 monoclonal antibodies (anti-CD3) are promising compounds for the treatment of type 1 diabetes (T1D). Anti-CD3 administration induces transient T-cell depletion both in preclinical and in clinical studies. Notably, said depletion mainly affects CD4+ but not CD8+ T cells. More...
ORGANISM(S): FoxP3-GFP NOD mouse 
2015-01-19 | E-MTAB-2437 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse CD4+ GFP- (Teff) and CD4+ GFP+ (Treg) T cells treated with IL-2
To obtain the molecular signature of the effect that the IL-2 therapeutic dose induces on T cells in vivo, we performed gene array analysis. Since it was critical to perform this analysis on highly purified Tregs and Teffs, and also because activated Teffs can acquire CD25 expression, we used GFP-Fo...
ORGANISM(S): Mus musculus 
2011-01-06 | E-MEXP-2530 | biostudies-arrayexpress
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