Sort   by:  
 Page size 
GenomicsAdamts1 Promotes Cyst Expansion in Polycystic Kidney Disease
Adamts1 Promotes Cyst Expansion in Polycystic Kidney Disease
PRJNA1127459 | ENA
GenomicsNuclear accumulation of ADAMTS1 zymogen: A novel mechanism promoting chemoresistance and metastasis in breast cancer
Nuclear accumulation of ADAMTS1 zymogen: A novel mechanism promoting chemoresistance and metastasis in breast cancer
PRJNA1312462 | ENA
TranscriptomicsAdamts1 Adipocyte Progenitor Cell (APC) expression profile
Expression profiling comparing primary adipocyte progenitor cells from Adamts1 transgenic mice to wild-type littermates
ORGANISM(S): Mus musculus 
2016-12-06 | GSE71427 | GEO
GenomicsNuclear accumulation of ADAMTS1 zymogen: A novel mechanism promoting chemoresistance and metastasis in breast cancer [RNA-Seq]
Nuclear accumulation of ADAMTS1 zymogen: A novel mechanism promoting chemoresistance and metastasis in breast cancer [RNA-Seq]
PRJNA1314843 | ENA
TranscriptomicsAdamts1 Promotes Cyst Expansion in Polycystic Kidney Disease
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by mutations in either the PKD1 or PKD2 genes leading to progressive cyst growth and often ESKD. We have previously demonstrated that with loss of Pkd1 the tubules can enlarge without an increase in tubular cell numbers, suggestin...
ORGANISM(S): Mus musculus 
2024-09-30 | GSE270531 | GEO
TranscriptomicsProtease profiling of liver fibrosis reveals the ADAM metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of transforming growth factor beta
During chronic liver disease, tissue remodeling leads to dramatic changes and accumulation of matrix components. Matrix metalloproteases and their inhibitors have been involved in the regulation of matrix degradation. However, the role of other proteases remains incompletely defined. We undertook a ...
ORGANISM(S): Homo sapiens 
2012-01-05 | E-GEOD-24667 | biostudies-arrayexpress
UnknownMacrophage-released ADAMTS1 promotes muscle stem cell activation.
Not available
S-EPMC5610267 | biostudies-literature
GenomicsNuclear accumulation of ADAMTS1 zymogen: A novel mechanism promoting chemoresistance and metastasis in breast cancer
Chemoresistance and metastasis are the primary causes of mortality in patients with breast cancer. Here, we demonstrated that the metalloproteinase ADAMTS1 is upregulated in chemotherapy-treated and metastatic breast cancer samples. Mechanistically, the zymogen form of ADAMTS1 undergoes nuclear tran...
ORGANISM(S): Homo sapiens 
2025-09-03 | GSE306824 | GEO
UnknownISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1.
Not available
S-EPMC10176748 | biostudies-literature
UnknownThe ADAMTS1 protease gene is required for mammary tumor growth and metastasis.
Not available
S-EPMC3260838 | biostudies-literature
Sort   by:  
 Page size