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We previously showed in NHP studies that a protective gene signature that was enriched in uninfected monkeys after Ad26/gp140 vaccination also associated with higher magnitude of ADCP (Ehrenberg et al., 2019). In the RV144 human trial a number of immunological parameters were previously measured as ...
ORGANISM(S): Homo sapiens 
2021-09-23 | GSE181932 | GEO
Therapeutic antibodies trigger antibody-dependent cellular cytotoxicity (ADCC) of cancer cells and also their antibody-dependent cellular phagocytosis (ADCP) by tumor-associated macrophages (TAMs). We report here our unexpected finding that TAMs that have undergone ADCP of tumor cells induced by the...
ORGANISM(S): Homo sapiens 
2018-09-04 | GSE119342 | GEO
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