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TranscriptomicsFGF2 stimulation experiment with CD1 mouse embryonic fibroblasts
Mouse embryonic fibroblasts stimulated with 40 ng/ml of FGF2 in conventional hES cell medium were analysed on whole-genome expression chips to reveal altered expression of genes encoding secreted proteins. as detailed for the individual samples
ORGANISM(S): Mus musculus 
2010-06-10 | E-GEOD-5435 | biostudies-arrayexpress
TranscriptomicsFGF2 stimulation experiment with NMRI mouse embryonic fibroblasts
Mouse embryonic fibroblasts stimulated with 40 ng/ml of FGF2 in conventional hES cell medium were analysed on whole-genome expression chips to reveal altered expression of genes encoding secreted proteins. as detailed for the individual samples
ORGANISM(S): Mus musculus 
2010-06-10 | E-GEOD-5436 | biostudies-arrayexpress
TranscriptomicsFGF inhibition directs BMP4-mediated differentiation of Human Embryonic Stem Cells to syncytiotrophoblast
Bone morphogenetic protein (BMP) signaling is known to support differentiation of human embryonic stem cells (hESCs) into mesoderm and extraembryonic lineages, whereas other signaling pathways can largely influence this lineage specification. Here, we set out to reinvestigate the influence of ACTIVI...
ORGANISM(S): Homo sapiens 
2012-10-17 | E-GEOD-30125 | biostudies-arrayexpress
TranscriptomicsHuman Induced Pluripotent Stem Cells Harbor Homoplasmic and Heteroplasmic Mitochondrial DNA Mutations While Maintaining human embryonic stem cells-like Metabolic Reprogramming
Gene expression analyis of two hESCs, two human neonatal fibroblasts, and four human iPSCs generated with retroviral transduction using the OSKM cocktail. Total mRNA obtained from two fibroblasts (BJ and HFF1), two hESCs (H1 and H9), two BJ-derived iPSCs (iB4 and iB5), and two HFF1-derived iPSCs (iP...
ORGANISM(S): Homo sapiens 
2011-07-08 | E-GEOD-26575 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of immediate early events in mRNA-mediated cellular reprogramming of human foreskin fibroblasts
In this study human neonatal foreskin fibroblasts (HFF1 and BJ) were lipofected with an equal mixture of human reprogramming factor-encoding mRNAs. The cells were lysed and total RNA was harvested 24 hours post-transfection. Gene regulation was evaluated with respect to corresponding mock-transfecte...
ORGANISM(S): Homo sapiens 
2012-07-03 | E-GEOD-34943 | biostudies-arrayexpress
TranscriptomicsValproic Acid Confers Functional Pluripotency to Human Amniotic Fluid Stem Cells in a Transgene-free Approach
Induced pluripotent stem cells (iPSCs) with potential for therapeutic applications can be derived from somatic cells via ectopic expression of a set of limited and defined transcription factors. However, due to risks of random integration of the reprogramming transgenes into the host genome, the low...
ORGANISM(S): Homo sapiens 
2012-07-23 | E-GEOD-26940 | biostudies-arrayexpress
ModelsChavez2009 - a core regulatory network of OCT4 in human embryonic stem cells
Chavez2009 - a core regulatory network of OCT4 in human embryonic stem cells A core OCT4-regulated network has been identified as a test case, to analyase stem cell characteristics and cellular differentiation. This model is described in the article: ...
2005-01-01 | MODEL1305010000 | BioModels
TranscriptomicsAssociation between in vivo bone formation and ex vivo migration capacity of human bone marrow stromal cells
Introduction: There is a clinical need for developing systemic transplantation protocols for use of human skeletal stem cells (also known bone marrow stromal stem cells) (hBMSC) in tissue regeneration. In systemic transplantation studies, only a limited number of hBMSC home to injured tissues sugges...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-69358 | biostudies-arrayexpress
TranscriptomicsFunctional Comparison of Chronological and In Vitro Aging: Differential Role of the Cytoskeleton and Mitochondria in Mesenchymal Stromal Cells
Mesenchymal stromal cells (MSCs) are of high relevance for the regeneration of mesenchymal tissues such as bone and cartilage. The promising role of MSCs in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor age, t...
ORGANISM(S): Rattus norvegicus 
2013-01-05 | E-GEOD-36596 | biostudies-arrayexpress
UnknownSecretome Analysis of Mesenchymal Stem Cell Factors Fostering Oligodendroglial Differentiation of Neural Stem Cells In Vivo.
Not available
S-EPMC7352621 | biostudies-literature
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