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Adjuvant is an important component of vaccines However, given the limitation of existing adjuvants in variety and mechanism, developing a unique and effective adjuvant is urgently needed for clinal applications. Recent studies have implicated that the mevalonate pathway plays an essential role in va...
2026-03-03 | MTBLS11696 | MetaboLights
The effect of selected adjuvants on the mRNA expression of peritoneal exudate cells.
ORGANISM(S): Mus musculus 
Analysis of whole mouse muscle gene expression signature induced by in-vivo intramuscularly administration of MF59, CpG, MF59+CpG, alum and PBS. MF59 and alum are licensed human vaccine adjuvants; CpG is a TLR-agonist adjuvant.
ORGANISM(S): Mus musculus 
Vaccine research today is focused on using safer, highly purified or recombinant antigens with poor immunogenicity, which has created a need for potent adjuvants. Rational design of effective and safe mucosal adjuvants for human use necessitates a thorough understanding of the mode of action of succ...
ORGANISM(S): Mus musculus 
Characterizing adjuvants’ effects at the murine immunoglobulin repertoire level
Transcriptomic signatures induced by single versus dual lipoparticle-formulated adjuvants
Genomics
studys on adjuvants
Differential gene expression in mouse whole blood and lymph nodes at 4 different timepoints following administration of different vaccine/adjuvants combinations
ORGANISM(S): Mus musculus 
2017-01-09 | GSE85339 | GEO
This proteomics data are generated from mouse skin treated with physical radiofrequency adjuvant and common chemical adjuvants, such as AddaVax, MPL, Alum, MPL/Alum.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-11-09 | MSV000090681 | MassIVE
Molecular signatures of clinically tested vaccine adjuvants
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